Results 111 to 120 of about 118,027 (327)

Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis   +4 more
wiley   +1 more source

Procjena opasnosti pri radu specijalista za zaštitu zdravlja divljih životinja u Indiji. [PDF]

open access: yes, 2011
A study to assess the levels of various threats and awareness among wildlife health professionals was carried out using a self administered questionnaire that focused on personal health details, the extent of exposure to various hazards, safety measures ...
Anupam Srivastav, Parag Nigam
core   +2 more sources

Exonic Variation in HLA‐C, CFB, and TAP2 Associated With Increased Risk for Comorbid Crohn's Disease and Psoriasis

open access: yesInternational Journal of Dermatology, EarlyView.
Our recent work established an association between high polygenic risk scores (PRSes) for both psoriasis and Crohn's disease with the development of comorbid disease. The protein‐coding genetic variation associated with the development of comorbid psoriasis and Crohn's disease is understudied.
Vikram R. Shaw   +6 more
wiley   +1 more source

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes

open access: yesInternational Journal of Immunogenetics, EarlyView.
ABSTRACT The etiology of ankylosing spondylitis (AS) is complex and not yet fully understood. Interleukin‐6 (IL‐6), vitamin D and the vitamin D receptor (VDR) play an important role in modulating immune response, and Torque teno virus is considered a marker of immune status. This case–control study aimed to investigate the predisposition to AS. A total
Dănuț Cimponeriu   +6 more
wiley   +1 more source

Infectious lesions of the spine: draft national clinical guidelines

open access: yesХирургия позвоночника, 2019
A draft national clinical guidelines for spinal infectious lesions are submitted for discussion. Clinical guidelines are intended to optimize the diagnosis and treatment of infectious spondylitis and based on modern information about the pathology ...
Aleksandr Yu. Mushkin   +4 more
doaj   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

open access: yesImmunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Beware of Brucella Spondylitis Following Vertebroplasty: An Unusual Case of Osteoporotic Vertebral Compression Fracture

open access: yesInfection and Drug Resistance, 2022
Jie Wang, Qiang Zhang Department of Orthopedics, Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, People’s Republic of ChinaCorrespondence: Qiang Zhang, Email zhangqianggk@sina.comAbstract: There are two main types of infectious ...
Wang J, Zhang Q
doaj  

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami   +6 more
wiley   +1 more source

A Case Report of Tuberculosis with Extrapulmonary Manifestations

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2019
BACKGROUND AND OBJECTIVE: Mycobacterium tuberculosis affects millions of people in the world and Iran is one of the endemic areas. This disease has a wide range of manifestations, which is pulmonary in 80 – 85% of cases and extrapulmonary in 15 – 20% of ...
S Gazeran, M Emami, F Zemorshidi
doaj  

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