Results 91 to 100 of about 76,712 (310)

MRI of the axial skeleton in spondyloarthritis : the many faces of new bone formation [PDF]

, 2019
Spondyloarthritis has two hallmark features: active inflammation and structural lesions with new bone formation. MRI is well suited to assess active inflammation, but there is increasing interest in the role of structural lesions at MRI.
Carron, Philippe, Elewaut, Dirk, Herregods, Nele, Jans, Lennart, Jaremko, Jacob L, Laloo, Frederiek, Van den Bosch, Filip, Verstraete, Koenraad   +7 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

A 17 year old with isolated proximal tibiofibular joint arthritis

Pediatric Rheumatology Online Journal, 2013
The proximal tibiofibular joint (TFJ) is rarely affected in rheumatic diseases, and we frequently interpret pain of the lateral knee as the result of overuse or trauma.
Canna Scott W, Chauvin Nancy A, Burnham Jon M   +2 more
doaj   +1 more source

The perspective of people with axial spondyloarthritis regarding physiotherapy : room for the implementation of a more active approach [PDF]

, 2019
Objectives. Physiotherapy is recommended in the management of people with axial spondyloarthritis (axSpA), with new insights into its preferred content and dosage evolving.
Goekoop-Ruiterman, Yvonne P M, Meichtry, André, Niedermann Schneider, Karin, Osthoff, Anne-Kathrin Rausch, Peeters, Andreas J, van der Giesen, Florus, van Gaalen, Floris A, Vliet Vlieland, Theodora P M, Walker, Beatrice   +8 more
core   +1 more source

Epigenetics of spondyloarthritis

Joint Bone Spine, 2020
Spondyloarthritis (SpA) is a chronic inflammatory disorder resulting from a combination of genetic predisposition and environmental factors. Despite recent advances, a substantial fraction of its genetic basis remains poorly understood. Several mechanisms have been proposed to account for this unexplained heritability, including epigenetics which can ...
Cherqaoui, Bilade, Crémazy, Frédéric, Hue, Christophe, Garchon, Henri-Jean, Breban, Maxime, Costantino, Félicie   +5 more
openaire   +3 more sources

Measuring the Impact: MRI Response of Sacroiliac Joints to TNF Inhibitors in Youth with Axial Disease

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Tuberculin skin test repetition after TNF-α inhibitors in patients with chronic inflammatory arthritis: a long-term retrospective cohort in endemic area

Advances in Rheumatology
Objectives To evaluate the tuberculin skin test (TST) conversion in chronic inflammatory arthropathies (CIA) patients on TNFα inhibitors (TNFi) and without previous latent tuberculosis infection (LTBI) treatment.
Vanessa de Oliveira Magalhães, Karina Rossi Bonfiglioli, Carina More Frade Gomes, Eloisa Bonfá, Ana Cristina de Medeiros-Ribeiro, Carla Gonçalves S. Saad, Marcelo de Medeiros Pinheiro   +6 more
doaj   +1 more source

Diagnositic value of pelvic enthesitis on MRI of the sacroiliac joints in enthesitis related arthritis [PDF]

, 2015
Background: To determine the prevalence and diagnostic value of pelvic enthesitis on MRI of the sacroiliac (SI) joints in enthesitis related arthritis (ERA).
Baraliakos, X., Dehoorne, Jo, Elewaut, Dirk, Herregods, Nele, Jans, Lennart, Jaremko, J. L., Joos, R, PATTYN, EVA, Van den Bosch, Filip, Van Vlaenderen, J, Verstraete, Koenraad   +10 more
core   +1 more source

Unmet Needs in Spondyloarthritis: Imaging in Axial Spondyloarthritis

The Journal of Rheumatology
Imaging biomarkers in axial spondyloarthritis (axSpA) are currently the most specific biomarkers for the diagnosis of this condition. Despite advances in imaging, from plain radiographs—which detect only damage—to magnetic resonance imaging (MRI)—which identifies disease activity and structural change—there are still many challenges that remain ...
Lianne S. Gensler, Lennart Jans, Sharmila Majumdar, Denis Poddubnyy   +3 more
openaire   +2 more sources

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source