Results 61 to 70 of about 76,712 (310)

Janus kinase inhibitors in immunoinflammatory diseases: 10 years of clinical practice in rheumatology

Научно-практическая ревматология, 2022
Despite great advances in the diagnosis and treatment of Immune-mediated inflammatory diseases (IMIDs), which have led to a significant improvement in the prognosis in many patients, the central medical problems of this pathology – restoring the quality ...
E. L. Nasonov, T. V. Korotaeva
doaj   +1 more source

Osteoimmunology of Spondyloarthritis

International Journal of Molecular Sciences, 2023
The mechanisms underlying the development of bone damage in the context of spondyloarthritis (SpA) are not completely understood. To date, a considerable amount of evidence indicates that several developmental pathways are crucially involved in osteoimmunology.
Angelo, Fassio, Fabiola, Atzeni, Maurizio, Rossini, Valeria, D'Amico, Francesco, Cantatore, Maria Sole, Chimenti, Chiara, Crotti, Bruno, Frediani, Andrea, Giusti, Giusy, Peluso, Guido, Rovera, Palma, Scolieri, Vincenzo, Raimondo, Davide, Gatti, , On Behalf Of The Study Group On Osteoporosis And Skeletal Metabolic Diseases Of The Italian Society Of Rheumatology   +14 more
openaire   +4 more sources

Comorbid infections in patients with spondyloarthritis who received modern antirheumatic therapy (preliminary data)

Научно-практическая ревматология, 2022
Actuality. Data on the prevalence of comorbid infections (CI) in patients with spondyloarthritis (SpA) are few. Risk factors for CI has not been sufficiently studied.Objective.
M. M. Baranova, N. V. Muravyeva, B. S. Belov, S. I. Glukhova, T. V. Korotaeva   +4 more
doaj   +1 more source

Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis and Persistent Pain: A Randomized Controlled Trial. [PDF]

Arthritis Care Res (Hoboken)
Objective Axial spondyloarthritis (axSpA) is often associated with persistent pain despite effective anti‐inflammatory treatment. Digital health applications (DHAs) provide innovative approaches to address multidimensional aspects of persistent pain through psychological and behavioral strategies. The aim of this study was to assess the impact of a DHA
Kiefer D, Sonkaya Y, Krause D, Voglau M, Mintrop B, Redeker I, Baraliakos X, Kiltz U.   +7 more
europepmc   +2 more sources

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis [PDF]

, 2009
Objectives Th17 cells are an effector T-cell population that plays a role in chronic inflammatory conditions and is dependent on IL-23 for their survival and expansion. More recently, a genetic association was discovered between polymorphisms in the gene
De Keyser, Filip, De Vos, Martine, Elewaut, Dirk, Jacques, Peggy, Kruithof, Elli, Melis, Lode, Mielants, Herman, VANDOOREN, BERNARD, Verbruggen, August   +8 more
core   +1 more source

Effect of Secukinumab Versus Adalimumab Biosimilar on Radiographic Progression in Patients With Radiographic Axial Spondyloarthritis: Results From a Head‐to‐Head Randomized Phase IIIb Study

Arthritis & Rheumatology
Spinal radiographic progression is an important outcome in radiographic axial spondyloarthritis (SpA). The objective of the phase IIIb SURPASS study was to compare spinal radiographic progression in patients with radiographic axial SpA treated with ...
X. Baraliakos, Mikkel Østergaard, Denis Poddubnyy, D. van der Heijde, A. Deodhar, Pedro M. Machado, V. Navarro-Compán, Kay-Geert A Hermann, M. Kishimoto, Eun Young Lee, L. Gensler, U. Kiltz, M. Eigenmann, P. Pertel, A. Readie, H. Richards, B. Porter, J. Braun   +17 more
semanticscholar   +1 more source

Diagnostic delay in axial spondyloarthritis: a systematic review and meta-analysis.

Rheumatology, 2021
BACKGROUND Delay to diagnosis in axial SpA (axSpA) is longer than in many other rheumatic diseases. Prolonged delay is associate with poorer outcomes, including functional impairment and quality of life.
S. Zhao, B. Pittam, N. Harrison, Ashar E. Ahmed, N. Goodson, D. Hughes   +5 more
semanticscholar   +1 more source

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

Arthritis Care &Research, EarlyView.
Objective Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla, Timothy G. Brandon, Dmitry Khrichenko, Rui Xiao, Nancy A. Chauvin, Asef Khwaja, Pamela F. Weiss   +6 more
wiley   +1 more source

Histopathology of the gut in rheumatic diseases [PDF]

, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F., Ferrante A., Guggino G., Macaluso F., Rizzo A.   +4 more
core   +1 more source

Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study

RMD Open, 2021
Objectives To characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world. Methods Cross-sectional study with 24 participating countries.
C. López-Medina, A. Moltó, J. Sieper, T. Duruöz, U. Kiltz, B. Elzorkany, N. Hajjaj-Hassouni, R. Burgos-Vargas, J. Maldonado-Cocco, N. Ziadé, M. Gavali, V. Navarro-Compán, S. Luo, S. Monti, K. Tae-Jong, M. Kishimoto, F. Pimentel-Santos, J. Gu, R. Schiotis, F. Gaalen, P. Géher, M. Magrey, Sebastián E Ibáñez, W. Bautista-Molano, W. Maksymowych, P. Machado, R. Landewé, D. Heijde, M. Dougados, Twitter Nelly   +29 more
semanticscholar   +1 more source