Results 61 to 70 of about 62,455 (259)

Silencing SOCS3 Markedly Deteriorates Spondyloarthritis in Mice Induced by Minicircle DNA Expressing IL23

Frontiers in Immunology, 2018
Objective: Despite extensive studies, the precise mechanism underlying spondyloarthritis, especially ankylosing spondylitis, remains elusive. This study aimed to develop an ideal animal model for an insight into mechanism of spondyloarthritis and ...
Yuhai Chen, Jing Ouyang, Ruoxiang Yan, Mohamed Hassan Maarouf, Mohamed Hassan Maarouf, Mohamed Hassan Maarouf, Xuefei Wang, Xuefei Wang, Biao Chen, Biao Chen, Shasha Liu, Shasha Liu, Jiayue Hu, Guijie Guo, Jing Zhang, Sheng-Ming Dai, Huji Xu, Ji-Long Chen   +17 more
doaj   +1 more source

The perspective of people with axial spondyloarthritis regarding physiotherapy : room for the implementation of a more active approach [PDF]

, 2019
Objectives. Physiotherapy is recommended in the management of people with axial spondyloarthritis (axSpA), with new insights into its preferred content and dosage evolving.
Goekoop-Ruiterman, Yvonne P M, Meichtry, André, Niedermann Schneider, Karin, Osthoff, Anne-Kathrin Rausch, Peeters, Andreas J, van der Giesen, Florus, van Gaalen, Floris A, Vliet Vlieland, Theodora P M, Walker, Beatrice   +8 more
core   +1 more source

Uveitis in spondyloarthritis [PDF]

Therapeutic Advances in Musculoskeletal Disease, 2020
Uveitis is the most frequent extra-articular manifestation of axial spondyloarthritis (SpA), occurring in up to one-third of the patients. In the majority of patients, uveitis is acute, anterior and unilateral and presents with photosensitivity, sudden onset of pain and blurred vision. Topical steroids are an effective treatment; however, recurrent or
Judith Rademacher, Denis Poddubnyy, Uwe Pleyer   +2 more
openaire   +3 more sources

Enthesopathy in spondyloarthritis: the literature review

Научно-практическая ревматология, 2021
The article presents data on epidemiology, pathogenesis, clinical manifestations, diagnosis and therapy of enthesopathy in spondyloarthritis. The approaches to assessment of this pathology are examined and detailed, modern clinical and ultrasound indices
D. I. Abdulganieva, E. R. Kirillova, I. F. Fairushina, G. R. Gaynullina, R. Z. Abdrakipov, R. G. Mukhina, E. I. Mukhametshina   +6 more
doaj   +1 more source

Randomized controlled trial of adalimumab in patients with nonpsoriatic peripheral spondyloarthritis [PDF]

, 2015
Objective. To evaluate the efficacy and safety of adalimumab in patients with active nonpsoriatic peripheral spondyloarthritis (SpA). Methods. ABILITY-2 is an ongoing phase III, multicenter study of adalimumab treatment.
Karunaratne, P Mahinda, Mease, Philip, Pangan, Aileen L, Rahman, Proton, Sieper, Joachim, Van den Bosch, Filip   +5 more
core   +1 more source

High Healthcare Utilization Preceding Diagnosis with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective Though early diagnosis improves long‐term outcomes, Juvenile Idiopathic Arthritis (JIA) patients often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize healthcare utilization in the year preceding diagnosis.
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R Rasooly, Pamela F Weiss   +5 more
wiley   +1 more source

A 17 year old with isolated proximal tibiofibular joint arthritis

Pediatric Rheumatology Online Journal, 2013
The proximal tibiofibular joint (TFJ) is rarely affected in rheumatic diseases, and we frequently interpret pain of the lateral knee as the result of overuse or trauma.
Canna Scott W, Chauvin Nancy A, Burnham Jon M   +2 more
doaj   +1 more source

Histopathology of the gut in rheumatic diseases [PDF]

, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F., Ferrante A., Guggino G., Macaluso F., Rizzo A.   +4 more
core   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Biomarkers for successful tapering of a tumor necrosis factor inhibitor in patients with radiographic axial spondyloarthritis: A pilot study

SAGE Open Medicine
Background: Tumor necrosis factor inhibitors are the most widely used biological disease-modifying antirheumatic drugs for radiographic axial spondyloarthritis.
Hong Ki Min, Ji-Yeon Lee
doaj   +1 more source