Results 81 to 90 of about 315,724 (308)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Circular RNAs in hepatocellular carcinoma: Functions and implications

open access: yesCancer Medicine, 2018
At present, as hotspot members of the noncoding RNA network, circular RNAs (circRNAs) with distinct properties and diverse pathophysiological functions are being increasingly delineated.
Liyun Fu   +4 more
doaj   +1 more source

Imidazole Alkaloids from the South China Sea Sponge Pericharax heteroraphis and Their Cytotoxic and Antiviral Activities

open access: yesMolecules, 2016
Marine sponges continue to serve as a rich source of alkaloids possessing interesting biological activities and often exhibiting unique structural frameworks.
Kai-Kai Gong   +4 more
doaj   +1 more source

The bromotyrosine derivative Ianthelline isolated from the Arctic marine sponge Stryphnus fortis inhibits marine micro- and macrobiofouling [PDF]

open access: yes, 2014
International audienceThe inhibition of marine biofouling by the bromotyrosine derivative ianthelline, isolated from the Arctic marine sponge Stryphnus fortis, is described. All major stages of the fouling process are investigated.
Andersen, Jeanette H.   +9 more
core   +3 more sources

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin   +5 more
wiley   +1 more source

Eutrophication has no short-term effect on the Cymbastela stipitata holobiont

open access: yesFrontiers in Microbiology, 2014
Levels of nitrogen in coastal areas have been rapidly increasing due to accumulative inputs of sewage and terrigenous sediments carrying fertilizers. Sponges have an immense filtering capacity and may be directly impacted (positively or negatively) by ...
Heidi M Luter   +2 more
doaj   +1 more source

A gradient model of vegetation and climate utilizing NOAA satellite imagery. Phase 1: Texas transect [PDF]

open access: yes
A climatological model/variable termed the sponge (a measure of moisture availability based on daily temperature maxima and minima, and precipitation) was tested for potential biogeograhic, ecological, and agro-climatological applications.
Greegor, D., Norwine, J.
core   +1 more source

MicroRNA-9 controls dendritic development by targeting REST [PDF]

open access: yes, 2014
MicroRNAs (miRNAs) are conserved noncoding RNAs that function as posttranscriptional regulators of gene expression. miR-9 is one of the most abundant miRNAs in the brain.
Akerblom   +95 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Immunization by subcutaneous implants of polyester-polyurethane sponges coupled with antigen

open access: yesBrazilian Journal of Medical and Biological Research, 1999
A new protocol is described for immunization of outbred Swiss mice. The procedure is based on subcutaneous implantation of antigen-coupled polyester-polyurethane sponges cut into disks of 10 mm in diameter vs 2 mm in thickness.
S.L. Lima   +6 more
doaj   +1 more source

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