Results 51 to 60 of about 2,521,623 (328)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
We disprove the Vafa-Witten theorem on the impossibility of spontaneously breaking parity in vector-like gauge field theories, identifying a mechanism driven by quantum fluctuations.
M. Aizenman+3 more
core +1 more source
Effect of Dual Reinforcement on Wear Resistance by Aluminum Compacts Reinforce by SiC, Al2O3 [PDF]
The producing composite materials of dual reinforcement in which the matrix material is aluminum reinforced with two types of ceramic particles : which are Alumina (50μmKeywordscomposite materials; wear test ; Al2O3; SiC ...
Mohammed Waheed, Hassan Abed
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
According to the famous Kibble-Zurek mechanism (KZM), the universality of spontaneous defect generation in continuous phase transitions (CPTs) can be understood by the critical slowing down.
Lee, Chaohong+3 more
core +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
A zero-mode mechanism for spontaneous symmetry breaking in a turbulent von K\'arm\'an flow [PDF]
We suggest that the dynamical spontaneous symmetry breaking reported in a turbulent swirling flow at $Re=40~000$ by Cortet et al., Phys. Rev. Lett., 105, 214501 (2010) can be described through a continuous one parameter family transformation (amounting ...
Daviaud, François+2 more
core +4 more sources
Spontaneous migration of periocular glass foreign body: An interesting case
The occurrence of soft-tissue foreign bodies (FBs) in and around the orbit is often seen after trauma. Wound exploration and removal of the embedded materials is the standard of care. Relevant investigations help to detect retained FBs in suspected cases.
Padma B Prabhu+2 more
doaj +1 more source
Spontaneous arterial bleeding is uncommon, and a mediastinal hematoma caused by spontaneous rupture of the internal thoracic artery has not been reported previously.
Jae Yang Park+2 more
doaj +1 more source