Results 51 to 60 of about 2,521,623 (328)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Spontaneous Parity Violation

open access: yes, 2005
We disprove the Vafa-Witten theorem on the impossibility of spontaneously breaking parity in vector-like gauge field theories, identifying a mechanism driven by quantum fluctuations.
M. Aizenman   +3 more
core   +1 more source

Effect of Dual Reinforcement on Wear Resistance by Aluminum Compacts Reinforce by SiC, Al2O3 [PDF]

open access: yesEngineering and Technology Journal, 2009
The producing composite materials of dual reinforcement in which the matrix material is aluminum reinforced with two types of ceramic particles : which are Alumina (50μmKeywordscomposite materials; wear test ; Al2O3; SiC ...
Mohammed Waheed, Hassan Abed
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Universal spatiotemporal dynamics of spontaneous superfluidity breakdown in the presence of synthetic gauge fields

open access: yes, 2016
According to the famous Kibble-Zurek mechanism (KZM), the universality of spontaneous defect generation in continuous phase transitions (CPTs) can be understood by the critical slowing down.
Lee, Chaohong   +3 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

A zero-mode mechanism for spontaneous symmetry breaking in a turbulent von K\'arm\'an flow [PDF]

open access: yes, 2014
We suggest that the dynamical spontaneous symmetry breaking reported in a turbulent swirling flow at $Re=40~000$ by Cortet et al., Phys. Rev. Lett., 105, 214501 (2010) can be described through a continuous one parameter family transformation (amounting ...
Daviaud, François   +2 more
core   +4 more sources

Spontaneous migration of periocular glass foreign body: An interesting case

open access: yesKerala Journal of Ophthalmology, 2017
The occurrence of soft-tissue foreign bodies (FBs) in and around the orbit is often seen after trauma. Wound exploration and removal of the embedded materials is the standard of care. Relevant investigations help to detect retained FBs in suspected cases.
Padma B Prabhu   +2 more
doaj   +1 more source

Spontaneous Rupture of the Internal Thoracic Artery Causing a Mediastinal Hematoma in a Patient with Alcoholic Liver Cirrhosis: A Case Report

open access: yesJournal of the Korean Society of Radiology, 2023
Spontaneous arterial bleeding is uncommon, and a mediastinal hematoma caused by spontaneous rupture of the internal thoracic artery has not been reported previously.
Jae Yang Park   +2 more
doaj   +1 more source

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