Results 81 to 90 of about 3,297,974 (375)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

9. The Importance of the Drawing in the Artistic Creation Process

open access: yesReview of Artistic Education, 2017
In this academic paper I want to highlight the importance of the drawing and its purpose in the visual artist's creative effort which is in full artistic activity.
Ştefănescu Mircea
doaj   +1 more source

Natural-Spontaneous Affective-Cognitive Dataset for Adult Students With and Without Asperger Syndrome

open access: yesIEEE Access, 2019
Any viable algorithm to infer affective states of individuals with autism requires natural and reliable data in real time and in an uncontrolled environment.
Amina Dawood   +2 more
doaj   +1 more source

Quantum Maxwell-Bloch equations for spatially inhomogeneous semiconductor lasers [PDF]

open access: yes, 1998
We present quantum Maxwell-Bloch equations (QMBE) for spatially inhomogeneous semiconductor laser devices. The QMBE are derived from fully quantum mechanical operator dynamics describing the interaction of the light field with the quantum states of the ...
A. Gatti   +29 more
core   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Ecogenomic insights into the resilience of keystone Blastococcus Species in extreme environments: a comprehensive analysis

open access: yesBMC Genomics
Background The stone-dwelling genus Blastococcus plays a key role in ecosystems facing extreme conditions such as drought, salinity, alkalinity, and heavy metal contamination. Despite its ecological significance, little is known about the genomic factors
Imed Sbissi   +3 more
doaj   +1 more source

Universal spatiotemporal dynamics of spontaneous superfluidity breakdown in the presence of synthetic gauge fields

open access: yes, 2016
According to the famous Kibble-Zurek mechanism (KZM), the universality of spontaneous defect generation in continuous phase transitions (CPTs) can be understood by the critical slowing down.
Lee, Chaohong   +3 more
core   +1 more source

Spontane Ösophagusruptur [PDF]

open access: yesPraxis, 2013
A 50 year old man presented to his local emergency department complaining of central chest pain and breathlessness that had begun after an episode of vomiting. Physical examination revealed diminished breath sounds at the left lung base and a temperature of 38°C. An erect chest radiograph showed a small, left sided pleural effusion.
A D Hollowood   +4 more
openaire   +4 more sources

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