Results 11 to 20 of about 5,153,334 (211)

Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease [PDF]

Lancet Neurology, 2021
Summary Sporadic Creutzfeldt-Jakob disease (sCJD) is a fatal and potentially transmissible neurodegenerative disease caused by misfolded prion proteins (PrPSc).
P. Hermann, B. Appleby, J. Brandel, B. Caughey, S. Collins, M. Geschwind, A. Green, S. Haïk, G. Kovacs, A. Ladogana, F. Llorens, S. Mead, N. Nishida, S. Pal, Piero Parchi, M. Pocchiari, K. Satoh, G. Zanusso, I. Zerr   +18 more
semanticscholar   +6 more sources

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]

Brain : a journal of neurology, 2009
Several molecular subtypes of sporadic Creutzfeldt–Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype.
Inga Zerr, K. Kallenberg, D. Summers, C. Romero, A. Taratuto, U. Heinemann, M. Breithaupt, D. Varges, B. Meissner, A. Ladogana, M. Schuur, S. Haïk, S. Collins, G. Jansen, G. Stokin, J. Pimentel, E. Hewer, D. Collie, Peter Smith, H. Roberts, J. Brandel, C. M. van Duijn, M. Pocchiari, C. Begué, P. Cras, R. Will, P. Sánchez-Juan   +26 more
semanticscholar   +4 more sources

Interlaboratory validation of cerebrospinal fluid α‐synuclein quantification in the diagnosis of sporadic Creutzfeldt‐Jakob disease [PDF]

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction Cerebrospinal fluid α‐synuclein level is increased in sporadic Creutzfeldt‐Jakob disease cases. However, the clinical value of this biomarker remains to be established.
Niels Kruse, Amanda Heslegrave, Vandana Gupta, Martha Foiani, Anna Villar‐Piqué, Matthias Schmitz, Sylvain Lehmann, Charlotte Teunissen, Kaj Blennow, Henrik Zetterberg, Brit Mollenhauer, Inga Zerr, Franc Llorens   +12 more
doaj   +2 more sources

Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease [PDF]

Emerging Infectious Diseases, 2014
We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease.
Jean Yves Douet, Saima Zafar, Armand Perret-Liaudet, Caroline Lacroux, Séverine Lugan, Naima Aron, Herve Cassard, Claudia Ponto, Fabien Corbière, Juan Maria Torres, Inga Zerr, Olivier Andreoletti   +11 more
doaj   +2 more sources

Progressive multifocal diffusion-weighted imaging hyperintensities in sporadic Creutzfeldt–Jakob disease with positive cerebrospinal fluid real-time quaking-induced conversion: a case report [PDF]

Journal of Medical Case Reports
Background Creutzfeldt–Jakob disease is a rare and invariably fatal neurodegenerative disorder classified among the prion diseases. Primarily affecting the brain, this condition precipitates neuronal cell demise, culminating in swiftly advancing dementia
Puyu Li, Wenjing Wang, Lingzhi Li, Keding Cheng, Ying Wang, Yuanyuan Li, Wei Xu   +6 more
doaj   +2 more sources

Atypical Presentation of Sporadic Creutzfeldt–Jakob Disease in a 59-Year-Old Male Patient [PDF]

BJPsych Open
Aims: Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder caused by prion proteins, leading to progressive brain damage. CJD has sporadic, variant, genetic, and iatrogenic forms, with sporadic being the most common, affecting 1–2 ...
Ruzaika Jaufer
doaj   +2 more sources

Validation of Revised International Creutzfeldt-Jakob Disease Surveillance Network Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease

JAMA Network Open, 2022
Key Points Question How sensitive and specific are the 2017 revised International Creutzfeldt-Jakob disease Surveillance Network diagnostic criteria for the diagnosis of sporadic Creutzfeldt-Jakob disease?
N. Watson, P. Hermann, A. Ladogana, A. Denouel, Simone Baiardi, E. Colaizzo, G. Giaccone, M. Glatzel, A. Green, S. Haïk, D. Imperiale, J. MacKenzie, F. Moda, Colin Smith, D. Summers, D. Tiple, Luana Vaianella, G. Zanusso, M. Pocchiari, I. Zerr, Piero Parchi, J. Brandel, S. Pal   +22 more
semanticscholar   +1 more source

The First Sporadic Creutzfeldt–Jakob Disease Case with a Rare Molecular Subtype VV1 and 1-Octapeptide Repeat Deletion in PRNP

Viruses, 2021
In the present manuscript, we report the clinical presentation and challenging diagnostic work-up of a sporadic Creutzfeldt–Jakob disease patient with confirmed VV1 subtype and heterozygous 1-octapeptide repeat deletion in the prion protein gene.
Aušrinė Areškevičiūtė, Eva Løbner Lund, Sabina Capellari, Piero Parchi, Christian Tersbøl Pinkowsky   +4 more
doaj   +1 more source

A discriminative event‐based model for subtype diagnosis of sporadic Creutzfeldt‐Jakob disease using brain MRI

Alzheimer's & Dementia, 2023
Sporadic Creutzfeldt‐Jakob disease (sCJD) comprises multiple subtypes (MM1, MM2, MV1, MV2C, MV2K, VV1, and VV2) with distinct disease durations and spatiotemporal cascades of brain lesions.
V. Venkatraghavan, Riccardo Pascuzzo, E. Bron, M. Moscatelli, M. Grisoli, A. Pickens, M. Cohen, L. Schonberger, P. Gambetti, B. Appleby, Stefan Klein, A. Bizzi   +11 more
semanticscholar   +1 more source

Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6

Neurobiology of Disease, 2023
Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is thought to occur when the cellular prion protein (PrPC) spontaneously misfolds and assembles into prion fibrils, culminating in fatal neurodegeneration.
Emma Jones, Elizabeth Hill, J. Linehan, Tamsin Nazari, Adam Caulder, G. Codner, Marie Hutchison, M. Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, H. Al-Doujaily, Malin K. Sandberg, Emmanuelle Viré, T. J. Cunningham, E. Asante, S. Brandner, J. Collinge, S. Mead   +18 more
semanticscholar   +1 more source