Results 181 to 190 of about 16,859 (216)

FLAIR MRI in sporadic Creutzfeldt–Jakob disease

Neurology, 2000
Creutzfeldt–Jakob disease (CJD) is a rapidly progressive and ultimately lethal dementing illness caused by an infectious protein named prion. Besides cognitive decline and psychiatric or behavioral abnormalities, various other neurologic deficits appear. Myoclonic jerking, in particular startle myoclonus, is seen most commonly.
A F, Vrancken, C J, Frijns, L M, Ramos
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Sporadic Creutzfeldt‐Jakob disease in two coworkers

Neurology, 1986
We report the coincidence of pathologically confirmed sporadic CJD in two unrelated schoolteachers who shared a school wing for 9 months. The first developed ataxia, tremulousness, and dementia 5 months after his last contact with his colleague. Diagnosis of CJD was made 2 months later by brain biopsy.
D B, Leiderman, K P, Decker, J, Borcich, D W, Choi   +3 more
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Risk factors for sporadic Creutzfeldt–Jakob disease

Annals of Neurology, 2008
AbstractObjectiveAlthough surgical transmission of Creutzfeldt–Jakob disease (CJD) has been demonstrated, these iatrogenic cases account for only a small proportion of all CJD cases. The majority are sporadic CJD (sCJD) cases of unknown cause. This study investigated whether some cases classified as sCJD might have an unrecognized iatrogenic basis ...
Hester J T, Ward, Dawn, Everington, Simon N, Cousens, Blaire, Smith-Bathgate, Michelle, Gillies, Katy, Murray, Richard S G, Knight, Peter G, Smith, Robert G, Will   +8 more
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Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease

Archives of Neurology, 1996
Making a clinical diagnosis of sporadic Creutzfeldt-Jakob disease relies on the evaluation of rapidly progressive dementia, ataxia, myoclonus, changes on the electroencephalogram, and other neurological signs. A definite diagnosis, however, is confined to cases that have been evaluated neuropathologically or by equivalent diagnostic techniques.
H A, Kretzschmar, J W, Ironside, S J, DeArmond, J, Tateishi   +3 more
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First symptom in sporadic Creutzfeldt–Jakob disease

Neurology, 2006
Established clinical criteria for diagnosing sporadic Creutzfeldt–Jakob disease (sCJD) rely heavily on symptoms that appear late in the disease, such as myoclonus or akinetic mutism.1,2 Previous studies identified cognitive, cerebellar, and behavioral symptoms as common early symptoms of CJD (table).3-6 These studies designated symptoms as “early ...
G D, Rabinovici, P N, Wang, J, Levin, L, Cook, M, Pravdin, J, Davis, S J, DeArmond, N M, Barbaro, J, Martindale, B L, Miller, M D, Geschwind   +10 more
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Neuropsychiatric symptoms in sporadic Creutzfeldt-Jakob disease

Brain
Abstract Although neuropsychiatric symptoms are not part of diagnostic criteria for sporadic Creutzfeldt-Jakob disease a few retrospective studies and our clinical experience have suggested they are prominent and often occur early. The objective of our study was to assess prospectively the neuropsychiatric features in sCJD
Jennifer Zitser, Sven Forner, Katherine Wong, Jin Chengshi, John Neuhaus, Jennifer Martindale, Ben J Raudabaugh, Kendra Benisano, Kelly Goodman-O’Leary, Stacy Metcalf, Mee-Ohk Kim, Marwa Hakimi, Isabelle E Allen, Bruce L Miller, Howard J Rosen, Katherine P Rankin, Michael D Geschwind   +16 more
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Variant or sporadic Creutzfeldt-Jakob disease?

The Lancet, 2010
1raises a major question for the future of variant Creutzfeldt-Jakob disease (vCJD) epidemics and suggests the occurrence of a second wave in the heterozygous population. In the reported case, diagnosis was based on clinical fi ndings and the results of magnetic resonance imaging (MRI).
J-P Brandel, D Galanaud, L Freeman, JL Laplanche, S Haik   +4 more
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Sporadic Creutzfeldt-Jakob Disease.

2011
The book chapter describes the epidemiology, genetics, clinical features, imaging and laboratory findings, histopathology (including immunohistochemistry and ultrastructure), molecular pathology, subtype classification and differential diagnosis of sporadic Creutzfeldt-Jakob disease, the most common human prion disease.
Budka H., Head M. W., Ironside J. W., Gambetti P., PARCHI, PIERO, Tagliavini F.   +5 more
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Classification of sporadic Creutzfeldt‐Jakob disease based on molecular and phenotypic analysis of 300 subjects

Annals of Neurology, 1999
Piero Parchi, A. Giese, S. Capellari, P. Brown, W. Schulz-Schaeffer, O. Windl, I. Zerr, H. Budka, N. Kopp, P. Piccardo, S. Poser, A. Rojiani, Nathalie Streichemberger, J. Julien, C. Vital, B. Ghetti, P. Gambetti, H. Kretzschmar   +17 more
semanticscholar   +1 more source

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

Nature, 1991
M. Palmer, Aidan J. Dryden, J. T. Hughes, J. Collinge   +3 more
semanticscholar   +1 more source