Results 11 to 20 of about 16,859 (216)

Sporadic Creutzfeldt–Jakob disease in Palestine with early ataxia and dysarthria: a case report [PDF]

BMC Neurology
Creutzfeldt–Jakob disease (CJD) is a rare and fatal neurodegenerative disorder caused by misfolded prion proteins. It progresses inexorably to death once clinical symptoms emerge.
Anita S. Bahbah, Esra’a O. Kurdi, Darwish M. Mosameh, Baraa M.M. Sharawi, Mohammed Damrah   +4 more
doaj   +2 more sources

Molecular classification of sporadic Creutzfeldt–Jakob disease [PDF]

Brain, 2003
According to the protein-only hypothesis of prion propagation, an abnormal isoform (designated PrP(Sc)) of the cellular prion protein (PrP(C)) is the principal or sole component of transmissible prions. However, the existence of multiple prion strains has been difficult to accommodate within this hypothesis.
Hill, Andrew F, Joiner, Susan, Wadsworth, Jonathan DF, Sidle, Katie CL, Bell, Jeanne E, Budka, Herbert, Ironside, James W, Collinge, John   +7 more
openaire   +4 more sources

Atypical Presentation of Sporadic Creutzfeldt–Jakob Disease in a 59-Year-Old Male Patient [PDF]

BJPsych Open
Aims: Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder caused by prion proteins, leading to progressive brain damage. CJD has sporadic, variant, genetic, and iatrogenic forms, with sporadic being the most common, affecting 1–2 ...
Ruzaika Jaufer
doaj   +2 more sources

The Phenotypic Spectrum of Sporadic Creutzfeldt-Jakob Disease Cortical Subtype. [PDF]

Ann Neurol
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Baiardi S, Vargiu CM, Appleby BS, Barria M, Bentivenga GM, Calì I, Carlà B, Cohen M, Giese A, Herms J, Kortelainen AM, Ladogana A, Mammana A, Ritchie D, Windl O, Capellari S, Parchi P.   +16 more
europepmc   +2 more sources

Sporadic Creutzfeldt-Jakob disease: clinical observation

Анналы клинической и экспериментальной неврологии, 2017
Creutzfeldt-Jakob disease (CJD) is a form of human prion diseases,fatal neurodegenerative conditions. They can be etiologicallydivided into sporadic, hereditary and acquired forms.Conformational change of the normal (cellular) form of prionprotein (PrPc)
A. V. Peresedova, N. I. Stoida, V. V. Gnezdizky, R. N. Konоvаlоv, O. S. Kоrеpina, I. A. Zavalishin   +5 more
doaj   +2 more sources

Chorea in Sporadic Creutzfeldt-Jakob Disease [PDF]

Journal of Movement Disorders, 2018
Ai Huey Tan, Tsun Haw Toh, Soon Chai Low, Si Lei Fong, Kah Kian Chong, Kee Wei Lee, Khean Jin Goh, Shen-Yang Lim   +7 more
doaj   +3 more sources

Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease.

Lancet Neurology, 2021
Sporadic Creutzfeldt-Jakob disease is a fatal neurodegenerative disease caused by misfolded prion proteins (PrPSc). Effective therapeutics are currently not available and accurate diagnosis can be challenging.
Peter Hermann, B. Appleby, J. Brandel, B. Caughey, S. Collins, M. Geschwind, A. Green, S. Haïk, G. Kovacs, A. Ladogana, F. Llorens, S. Mead, N. Nishida, S. Pal, Piero Parchi, M. Pocchiari, K. Satoh, G. Zanusso, I. Zerr   +18 more
semanticscholar   +1 more source

Validation of Revised International Creutzfeldt-Jakob Disease Surveillance Network Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease

JAMA Network Open, 2022
Key Points Question How sensitive and specific are the 2017 revised International Creutzfeldt-Jakob disease Surveillance Network diagnostic criteria for the diagnosis of sporadic Creutzfeldt-Jakob disease?
N. Watson, Peter Hermann, A. Ladogana, A. Denouel, Simone Baiardi, Elisa Colaizzo, G. Giaccone, M. Glatzel, A. Green, S. Haïk, D. Imperiale, J. MacKenzie, F. Moda, Colin Smith, D. Summers, D. Tiple, Luana Vaianella, G. Zanusso, M. Pocchiari, I. Zerr, Piero Parchi, J. Brandel, S. Pal   +22 more
semanticscholar   +1 more source

The First Sporadic Creutzfeldt–Jakob Disease Case with a Rare Molecular Subtype VV1 and 1-Octapeptide Repeat Deletion in PRNP

Viruses, 2021
In the present manuscript, we report the clinical presentation and challenging diagnostic work-up of a sporadic Creutzfeldt–Jakob disease patient with confirmed VV1 subtype and heterozygous 1-octapeptide repeat deletion in the prion protein gene.
Aušrinė Areškevičiūtė, Eva Løbner Lund, Sabina Capellari, Piero Parchi, Christian Tersbøl Pinkowsky   +4 more
doaj   +1 more source

Sporadic Creutzfeldt-Jakob Disease Mimicking Variant Creutzfeldt-Jakob Disease [PDF]

Archives of Neurology, 2003
The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons.To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD).Results of a
Jennifer, Martindale, Michael D, Geschwind, Stephen, De Armond, Geoffrey, Young, W P, Dillon, Roland, Henry, Jane H, Uyehara-Lock, David A, Gaskin, Bruce L, Miller   +8 more
openaire   +2 more sources