Results 41 to 50 of about 5,084,169 (167)

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source

Tissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levels

BMC Public Health, 2005
Background Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results.
Calero Miguel, Siden Åke, Mølbak Kåre, de Pedro-Cuesta Jesús, Rábano Alberto, Laursen Henning   +5 more
doaj   +1 more source

A case of sporadic Creutzfeldt-Jakob disease [PDF]

Romanian Journal of Neurology, 2012
Sporadic Creutzfeldt-Jakob disease (CJD) is a very rare and fatal disease caused by prions – proteins with unique characteristics and infective potential.
Raoul Pop, Arta Teodorescu, Maria Tanasie, Ruxandra Joikits, Roxana Gheoca, Mihaela Simu   +5 more
doaj   +1 more source

Changes in serum β‐synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Alba Cervantes González, Alejandra O Morcillo‐Nieto, Sara Serrano, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernández, Laura del Hoyo Soriano, Aida S Hernandez, Lucía Maure‐Blesa, Lídia Vaqué‐Alcázar, Javier Arranz, Íñigo Rodríguez‐Baz, Mateus R Aranha, Danna Perlaza, Laia Lidón, Daniel Alcolea, Alexandre Bejanin, María Carmona‐Iragui, Juan Fortea, Alberto Lleó, Markus Otto, Patrick Oeckl, Olivia Belbin   +23 more
wiley   +1 more source

The presence of valine at residue 129 in human prion protein accelerates amyloid formation [PDF]

, 2005
The polymorphism at residue 129 of the human PRNP gene modulates disease susceptibility and the clinicopathological phenotypes in human transmissible spongiform encephalopathies.
Tahiri-Alaoui, Abdessamad, Gill, A, Shaw, Michael, Shaw, M, Baskakov, I, Breydo, L, James, W, Tahiri-Alaoui, A, Disterer, Petra, Gill, Andrew, Baskakov, Ilia, Breydo, Leonid, Disterer, P, James, William   +13 more
core   +1 more source

Kat5 cKO mouse replicates biological domain signatures associated with Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) can be caused by autosomal‐dominant familial Alzheimer's disease (FAD) mutations in amyloid precursor protein (APP) or presenilin‐1 and 2, which form an enzyme substrate complex. KAT5 binds to the APP intracellular domain.
Greg A Cary, Jessica E. Young, Shannon E. Rose, Harald Frankowski, Heather Wilkins, Sai Sruthi Amirtha Ganesh, Julia Draper, Martin Darvas, Mark Bothwell, Suman Jayadev, Aquene N. Reid, Anna Greenwood, Allan I. Levey, Karina Leal, Gregory W. Carter, Jesse C. Wiley   +15 more
wiley   +1 more source

Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease

Case Reports in Neurological Medicine, 2018
Sporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system.
Sira Carrasco García de León, Juan Pablo Cabello, Ramón Ortiz, Julia Vaamonde   +3 more
doaj   +1 more source

Probable sporadic Creutzfeldt–Jakob disease mimicking focal epilepsy

Epilepsy and Behavior Case Reports, 2019
Creutzfeldt–Jakob disease (CJD) presents with seizures as an early symptom in only approximately 3% of cases. These seizures often present as nonconvulsive status epilepticus (NCSE) or epilepsia partialis continua (EPC).
Pei-Shan Hsiao, Yuan-Ming Lee, Fu-Sin Chu, Chao-Lin Lee, Fang-Chun Liu, Ping-Huang Tsai   +5 more
doaj   +1 more source

From Meat to Plant‐Based Products? The Enduring Impact of BSE on Beef Consumption

Agricultural Economics, Volume 57, Issue 4, July 2026.
ABSTRACT This study reassesses the impact of the historical BSE outbreak on EU diets, showing that consumption patterns shifted persistently even after policy actions eliminated the food safety risk. Utilizing advanced difference‐in‐differences techniques on 1980–2020 data, we demonstrate that while beef consumption exhibited a transient U‐shaped ...
Jader Velásquez, Shon Ferguson
wiley   +1 more source

ENFERMEDAD DE JAKOB-CREUTZFELDT. A PROPÓSITO DE UN CASO

Revistas Argentina de Medicina, 2017
La enfermedad de Jakob-Creutzfeuldt esporádica es la más común de las patologías priónicas humanas. Se presenta el caso de una paciente de 59 años de edad internada por trastornos conductuales cognitivos, acompañados de mioclonías y mutismo acinético.
Lucía González, José Fernández, Vanesa Aguilar, Silvana Tobares, Melisa Contreras, Livio Lanciani, Jimena Boccardo, Juan Carlos Giugni   +7 more
doaj   +2 more sources