Results 11 to 20 of about 5,376 (165)
A case of probable sporadic Creutzfeldt–Jakob disease
Family Medicine and Community Health, 2017 Creutzfeldt-Jakob Disease (CJD) is a fatal neurodegenerative brain disease. The author describes a case presented to primary care clinic whereby neuropsychiatric symptoms were the patient’s initial presentation which later manifested with declining ...
Norita Hussein
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Atypical Presentation of Sporadic Creutzfeldt–Jakob Disease in a 59-Year-Old Male Patient [PDF]
BJPsych OpenAims: Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder caused by prion proteins, leading to progressive brain damage. CJD has sporadic, variant, genetic, and iatrogenic forms, with sporadic being the most common, affecting 1–2 ...
Ruzaika Jaufer
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Chorea in Sporadic Creutzfeldt-Jakob Disease [PDF]
Journal of Movement Disorders, 2018 Ai Huey Tan +7 more
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A case of sporadic Creutzfeldt-Jakob disease [PDF]
Romanian Journal of Neurology, 2012 Sporadic Creutzfeldt-Jakob disease (CJD) is a very rare and fatal disease caused by prions – proteins with unique characteristics and infective potential.
Raoul Pop +5 more
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Understanding the Phenotypic Heterogeneity Within the Sporadic Creutzfeldt-Jakob Disease MV1 Subtype. [PDF]
Neuropathol Appl NeurobiolWe present the clinical, pathological and prion biophysical features of three atypical cases of the MV1 subtype of sporadic Creutzfeldt–Jakob disease (sCJD). We propose that these heterozygous cases exist on a spectrum ranging from MM1‐like to VV1‐like phenotypes and recommend that subtyping be performed at pH 6.9 to avoid missing atypical or mixed ...
Nemani SK +6 more
europepmc +2 more sources
Cerebrospinal Fluid Markers in Sporadic Creutzfeldt-Jakob Disease
International Journal of Molecular Sciences, 2011 Sporadic Creutzfeldt-Jakob disease (sCJD) is the commonest form of human prion diseases, accounting for about 85% of all cases. Current criteria for intra vitam diagnosis include a distinct phenotype, periodic sharp and slow-wave complexes at electroencephalography (EEG), and a positive 14-3-3-protein assay in the cerebrospinal fluid (CSF).
Gianluigi Zanusso +2 more
exaly +3 more sources
The Phenotypic Spectrum of Sporadic Creutzfeldt-Jakob Disease Cortical Subtype. [PDF]
Ann NeurolObjective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Baiardi S +16 more
europepmc +2 more sources
Viruses, 2021 In the present manuscript, we report the clinical presentation and challenging diagnostic work-up of a sporadic Creutzfeldt–Jakob disease patient with confirmed VV1 subtype and heterozygous 1-octapeptide repeat deletion in the prion protein gene.
Aušrinė Areškevičiūtė +4 more
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Sporadic Creutzfeldt-Jakob Disease Mimicking Variant Creutzfeldt-Jakob Disease [PDF]
Archives of Neurology, 2003 The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons.To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD).Results of a
Jennifer, Martindale +8 more
openaire +2 more sources
Acta Neuropathologica Communications, 2020 Mitochondrial dysfunction has been implicated in multiple neurodegenerative diseases but remains largely unexplored in Creutzfeldt-Jakob disease. Here, we characterize the mitochondrial respiratory chain at the individual neuron level in the MM1 and VV2 ...
Irene H. Flønes +7 more
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