Results 41 to 50 of about 16,859 (216)
JAMA Neurology, 2019 Importance Fluid biomarkers that can predict survival time in sporadic Creutzfeldt-Jakob disease (sCJD) will be critical for clinical care and for treatment trials.
A. Staffaroni +15 more
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Subtype Diagnosis of Sporadic Creutzfeldt–Jakob Disease with Diffusion Magnetic Resonance Imaging
Annals of Neurology, 2020 Sporadic Creutzfeldt–Jakob disease (sCJD) comprises several subtypes as defined by genetic and prion protein characteristics, which are associated with distinct clinical and pathological phenotypes.
A. Bizzi +12 more
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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
Acta Neuropathologica Communications, 2019 For the transmissible, neurogenerative family of prion diseases, few human models of infection exist and none represent structured neuronal tissue. Human cerebral organoids are self-organizing, three-dimensional brain tissues that can be grown from ...
B. Groveman +6 more
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Public health concerns regarding sporadic Creutzfeldt–Jakob disease in China: a case series
Journal of International Medical Research, 2019 In this study, we report three cases of sporadic Creutzfeldt–Jakob disease in China, two confirmed cases and one probable case. The aim of this study was to enrich the data regarding clinical and epidemiological features of this disease and to provide ...
Ru-Yi Zhou +12 more
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Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
Emerging Infectious Diseases, 2014 We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease.
Jean Yves Douet +11 more
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A prognostic model for overall survival in sporadic Creutzfeldt‐Jakob disease
Alzheimer's & Dementia, 2020 We developed a prognostic model for overall survival after diagnosis of sporadic Creutzfeldt‐Jakob disease (sCJD) using data from a German surveillance study.
F. Llorens +7 more
semanticscholar +1 more source
Young-onset sporadic Creutzfeldt–Jakob disease with atypical phenotypic features: a case report
Journal of Medical Case Reports, 2019 Background Sporadic Creutzfeldt–Jakob disease, with a mean survival of 6 months, is duly considered among the most fatal neurological disorders. Rapidly progressive dementia with multi-axial involvement of the nervous system is the known presentation ...
Durjoy Lahiri +5 more
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Sporadic Creutzfeldt–Jakob disease
, 2018 Sporadic Creutzfeldt-Jakob disease (CJD), the most common human prion disease, is generally regarded as a spontaneous neurodegenerative illness, arising either from a spontaneous PRNP somatic mutation or a stochastic PrP structural change. Alternatively, the possibility of an infection from animals or other source remains to be completely ruled out ...
Zerr, Inga, Parchi, Piero
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Rapidly Progressive Probable Sporadic Creutzfeldt-Jakob Disease
Cureus, 2022 Creutzfeldt-Jakob disease (CJD) is a rare, fatal brain infection caused by a human prion. Because CJD is associated with rapidly progressive neurological degeneration, it requires high suspicion for diagnosis. We report the case of a 79-year-old patient who presented with a rapidly progressive neurological clinical picture.
Elziny, Moustafa M, Elsaid, Shaimaa S
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Journal of Neurology Neurosurgery & Psychiatry, 2018 Objectives A blood-based biomarker of neuronal damage in sporadic Creutzfeldt-Jakob disease (sCJD) will be extremely valuable for both clinical practice and research aiming to develop effective therapies.
A. Thompson +6 more
semanticscholar +1 more source