Results 211 to 220 of about 160,756 (261)

Larval character evolution in Holometabola (Insecta)

open access: yesCladistics, EarlyView.
Abstract Larvae, a novel type of immature stage, are a crucial innovation of the Holometabola. Larval features therefore provide key evidence for reconstructing evolutionary transformations in this megadiverse group. Here we present the first formal reconstruction of larval character evolution, using maximum parsimony and Bayesian ancestral‐state ...
Rolf Georg Beutel, Jakub Goczał, Di Li
wiley   +1 more source

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

open access: yesCell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou   +8 more
wiley   +1 more source

The Plant‐Associated Fungus Chaetomium globosum Can Directly Infect and Kill Aphids

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Plant‐associated Chaetomium globosum strains caused direct infection and mortality in cotton aphids (Aphis gossypii) under different concentration‐dependent pathogenicity bioassays. Reinfection, aphid mortality, fungal re‐isolation, and molecular identification confirmed fulfillment of Koch's postulates for insect pathogenicity. These findings revealed
Janaina C. S. Cunha   +3 more
wiley   +1 more source

The transport of protein aggregates to the vacuole suggests a role for lipid droplets in waste disposal in Saccharomyces cerevisiae

open access: yesThe FEBS Journal, EarlyView.
Lipid droplets (LD) act as cellular ‘garbage trucks’ that transport cytosolic protein aggregates to the vacuole for degradation in yeast. Protein aggregates are docked to lipid droplets in a triacylglycerol‐dependent manner, transported through the cytoplasm, and transferred to the insoluble protein deposit (IPOD) at the vacuole.
Christoph Reiter   +15 more
wiley   +1 more source

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

open access: yesInternal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley   +15 more
wiley   +1 more source

Spatiotemporal expression of endospore appendages and cryo-EM insights into Ena1C-mediated S-ENA anchoring in Bacillus paranthracis. [PDF]

open access: yesSci Rep
Zegeye ED   +8 more
europepmc   +1 more source

16S ribosomal RNA modification drives transcript-specific translation efficiency. [PDF]

open access: yesCell Rep
Park ZM   +7 more
europepmc   +1 more source

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