Results 81 to 90 of about 21,077 (278)

An intravenous pancreatic cancer therapeutic: Characterization of CRISPR/Cas9n-modified Clostridium novyi-Non Toxic.

open access: yesPLoS ONE, 2023
Clostridium novyi has demonstrated selective efficacy against solid tumors largely due to the microenvironment contained within dense tumor cores. The core of a solid tumor is typically hypoxic, acidic, and necrotic-impeding the penetration of current ...
Kaitlin M Dailey   +9 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

Recent progress in proteins regulating the germination of Bacillus subtilis spores

open access: yesJournal of Bacteriology
Bacterial spores can remain dormant for years, but they maintain the ability to recommence life through a process termed germination. Although spore germination has been reviewed many times, recent work has provided novel conceptual and molecular ...
Tianyu Zhang   +4 more
doaj   +1 more source

Protein S-palmitoylation regulates different stages of meiosis in Schizosaccharomyces pombe

open access: yesLife Science Alliance, 2023
The vital role of S-palmitoylation in cell differentiation is demonstrated in the fission yeast by showing that the modification is required at multiple meiotic stages including mating and karyogamy.
Thanh-Vy Pham   +4 more
doaj   +1 more source

Factors affecting penicillium roquefortii (penicillium glaucum) in internally mould ripened cheeses: implications for pre-packed blue cheeses [PDF]

open access: yes, 2011
The amount and vivid colour of blue veins of internally mould ripened cheeses are desirable quality characteristics. It is therefore important that there is a sufficient amount of veining and that it maintains its blue appearance to be appealing to ...
ADAS   +10 more
core   +1 more source

The extension of the taxon cycle model to island plants: insights from the Canarian vascular flora

open access: yesBiological Reviews, EarlyView.
ABSTRACT Taxon cycle models describe eco‐evolutionary patterns of lineage colonization, diversification, and decline across archipelagos, inferring an important role for competition amongst ecologically similar taxa in driving concurrent niche changes.
José María Fernández‐Palacios   +2 more
wiley   +1 more source

Crystallization and preliminary X-ray analysis of the sporulation factor SpoIIAA in its native and phosphorylated forms [PDF]

open access: yes, 2001
Sporulation in Bacillus begins with an asymmetric cell division producing two progeny with identical chromosomes but different developmental fates. As such, it is a simple example of cellular differentiation.
Brannigan, J A   +3 more
core   +1 more source

Functionalizing Conductive Diamond: Recent Advance in Fabrication, Modifications, and Applications

open access: yesCarbon Energy, EarlyView.
This review highlights recent advancements in the synthesis, modification, and electrochemical applications of conductive diamond, particularly boron‐doped diamond (BDD). It emphasizes progress in fabrication methods, including CVD and HPHT, and explores modifications such as doping, surface terminations, and composite design, enabling significant ...
Ning Linghu, Xin Jiang, Jing Xu
wiley   +1 more source

Production of trehalose with trehalose synthase expressed and displayed on the surface of Bacillus subtilis spores

open access: yesMicrobial Cell Factories, 2019
Background Bacillus subtilis spores have been commonly used for the surface display of various food-related or human antigens or enzymes. For successful display, the target protein needs to be fused with an anchor protein. The preferred anchored proteins
Hongling Liu   +3 more
doaj   +1 more source

Key Challenges for Commercializing Perovskite–Silicon Tandem Solar Cells

open access: yesCarbon Energy, EarlyView.
This review discusses the scientific and technological challenges in advancing perovskite–silicon tandem solar cells (PSTSCs) from lab‐scale to commercial viability, focusing on long‐term stability, scalability, and economic feasibility. Key issues include intrinsic and extrinsic degradation factors, installation conditions, environmental impacts, and ...
Bilal Mehmood   +16 more
wiley   +1 more source

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