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Sporothrix and Sporotrichosis: A South African Perspective on a Growing Global Health Threat

open access: yesMycoses, Volume 67, Issue 10, October 2024.
ABSTRACT Sporotrichosis is a disease that arises from a fungal infection caused by members of the Ascomycete genus Sporothrix. The disease has a unique history in South Africa, due to an association with gold mines, where large numbers of mine workers were infected in the 1930s and 1940s.
Taygen Fuchs   +3 more
wiley   +1 more source

Thermotolerance in S. cerevisiae as a model to study extracellular vesicle biology

open access: yesJournal of Extracellular Vesicles, Volume 13, Issue 5, May 2024.
Extracellular vesicles (EVs) are thought to mediate intercellular communication for diverse physiology in all organisms. However, EVs are understudied in S. cerevisiae (baker's yeast), a model organism extensively used to resolve the molecular basis of fundamental eukaryotic biology. Here, Logan et al.
Curtis John Logan   +6 more
wiley   +1 more source

Feline sporotrichosis: a case series of itraconazole-resistant Sporothrix brasiliensis infection

open access: yesBrazilian Journal of Microbiology, 2020
The treatment of feline sporotrichosis is a challenge for veterinary clinicians since refractory cases may occur, due either to patient and/or to pharmacological management errors or due to the development of antifungal resistance. Thus, we aimed to describe the therapeutic history of feline cases infected by itraconazole-resistant Sporothrix ...
Ceres Cristina Tempel Nakasu   +8 more
openaire   +3 more sources

Two-dimensional gel electrophoresis data for proteomic profiling of Sporothrix yeast cells

open access: yesData in Brief, 2015
Sporotrichosis is a chronic infection of the skin and subcutaneous tissues of human and other mammals caused by a complex of cryptic dimorphic fungi in the plant-associated order Ophiostomatales.
Anderson Messias Rodrigues   +5 more
doaj   +1 more source

Tacrolimus Increases the Effectiveness of Itraconazole and Fluconazole against Sporothrix spp.

open access: yesFrontiers in Microbiology, 2017
Calcineurin inhibitors – such as the clinically used drug tacrolimus – are active against important fungal pathogens, particularly when combined with azoles.
Luana P. Borba-Santos   +6 more
doaj   +1 more source

Biological and Clinical Attributes of Sporothrix globosa, a Causative Agent of Sporotrichosis

open access: yesInfection and Drug Resistance, 2022
Nallely Nava-Pérez, Lisset G Neri-García, Oscar E Romero-González, Joshua A Terrones-Cruz, Laura C García-Carnero,* Héctor M Mora-Montes* Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de ...
Nava-Pérez N   +5 more
doaj  

Cutaneous Disseminated and Extracutaneous Sporotrichosis: Current Status of a Complex Disease

open access: yesJournal of Fungi, 2017
Sporotrichosis is an implantation or inoculation mycosis caused by species of Sporothrix schenckii complex; its main manifestations are limited to skin; however, cutaneous-disseminated, disseminated (visceral) and extracutaneous variants of ...
Alexandro Bonifaz   +1 more
doaj   +1 more source

Rapid Molecular Diagnosis of Sporotrichosis Directly from Biological Samples from a Reference Center in Brazil

open access: yesJournal of Fungi
The gold standard diagnosis of sporotrichosis is the isolation of Sporothrix sp. in culture media, but this is a time-consuming test that is susceptible to contamination and can be affected by the fungal load.
Amanda Gabriela da Silva   +7 more
doaj   +1 more source

Photodynamic inactivation strategies for maximizing antifungal effect against Sporothrix spp. and Candida albicans in an in vitro investigation.

open access: yesPLoS Neglected Tropical Diseases
BackgroundSporotrichosis is a zoonotic disease caused by the dimorphic fungus Sporothrix spp., leading to skin lesions that can, in some cases, progress and result in the death of infected individuals.
Amanda Regina Rocha   +4 more
doaj   +1 more source

Sporothrix brasiliensis and cats: understanding the disease and the promising potential of veterinary antifungal vaccination for a healthier future of both humans and animals

open access: yesAnimal Diseases
Sporotrichosis is a subcutaneous fungal infection caused by species of the Sporothrix genus that affects both humans and animals. Sporothrix brasiliensis is a dimorphic fungus that exists in a mycelial and conidial phase in nature and is a yeast in its ...
Marie Gabriele Santiago   +4 more
doaj   +1 more source

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