Results 81 to 90 of about 1,812 (159)

Sporothrix brasiliensis genetic toolbox

open access: yes, 2023
Sporotrichosis is the world's most prevalent and distributed subcutaneous mycosis. S. brasiliensis species is reported as the most virulent species, exhibiting the worst clinical manifestations, but the infection and virulence mechanisms of Sporothrix spp. still lack clarification.
openaire   +1 more source

Pentathiepins are an understudied molecular prism of biological activities

open access: yesArchiv der Pharmazie, Volume 357, Issue 12, December 2024.
Pentathiepins are cyclic sulfur‐rich compounds that possess remarkable chemical stability, unique structural features, and an extraordinary variety of biological activities. Nonetheless, they have only drawn the attention of the scientific community on a few occasions, generally after the serendipitous discovery of some of their properties. This review
Luca Pozzetti, Christopher R. M. Asquith
wiley   +1 more source

Fast diagnosis of sporotrichosis caused by Sporothrix globosa, Sporothrix schenckii, and Sporothrix brasiliensis based on multiplex real-time PCR

open access: yesPLOS Neglected Tropical Diseases, 2019
Le diagnostic précis de la sporotrichose et l'identification au niveau de l'espèce sont essentiels pour la santé publique et la gestion appropriée des patients. Par rapport aux méthodes d'identification morphologique, les tests de diagnostic moléculaire sont rapides et ont une sensibilité élevée et des processus opératoires normalisés.
Mingrui Zhang   +4 more
openaire   +4 more sources

Zoonotic feline sporotrichosis: a small case cluster in Perth, Western Australia, and a review of previous feline cases from Australia

open access: yesAustralian Veterinary Journal, Volume 102, Issue 12, Page 638-645, December 2024.
Sporotrichosis is caused by species of the fungus Sporothrix that affect human and several animal species. The transmission of sporotrichosis is classically from an environmental source following penetrating injury. The alternative zoonotic route has gained attention due to the rapid and significant spread of cat‐transmitted sporotrichosis in South ...
LHM Miranda   +4 more
wiley   +1 more source

Susceptibility and resistance of Sporothrix brasiliensis to branded and compounded itraconazole formulations

open access: yesBrazilian Journal of Microbiology, 2020
Itraconazole is the first drug of choice for the treatment of sporotrichosis and it is available at different concentrations for veterinary patients. However, therapeutic failure has been reported, limiting clinical treatment. This study evaluated the in vitro efficacy of brand-name and compounded itraconazole formulations against Sporothrix ...
Stefanie Bressan, Waller   +8 more
openaire   +3 more sources

Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic Cells

open access: yesInfection and Drug Resistance, 2023
Manuela Gómez-Gaviria,1 Iván Martínez-Duncker,2 Laura C García-Carnero,1 Héctor M Mora-Montes1 1Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Guanajuato, Guanajuato México; 2Laboratorio ...
Gómez-Gaviria M   +3 more
doaj  

Two-dimensional gel electrophoresis data for proteomic profiling of Sporothrix yeast cells

open access: yesData in Brief, 2015
Sporotrichosis is a chronic infection of the skin and subcutaneous tissues of human and other mammals caused by a complex of cryptic dimorphic fungi in the plant-associated order Ophiostomatales.
Anderson Messias Rodrigues   +5 more
doaj   +1 more source

Ibuprofen potentiates the itraconazole effect against Sporothrix brasiliensis and Sporothrix schenckii

open access: yes, 2018
The Sporothrix genus includes important human pathogens that cause sporotrichosis, neglected endemic mycoses with limited therapeutic options. In this study, we demonstrated that ibuprofen, an anti-inflammatory drug, increased the in vitro antifungal activity of itraconazole, the first choice treatment to human sporotrichosis.
Luana Borba-Santos   +2 more
openaire   +1 more source

Tacrolimus Increases the Effectiveness of Itraconazole and Fluconazole against Sporothrix spp.

open access: yesFrontiers in Microbiology, 2017
Calcineurin inhibitors – such as the clinically used drug tacrolimus – are active against important fungal pathogens, particularly when combined with azoles.
Luana P. Borba-Santos   +6 more
doaj   +1 more source

Biological and Clinical Attributes of Sporothrix globosa, a Causative Agent of Sporotrichosis

open access: yesInfection and Drug Resistance, 2022
Nallely Nava-Pérez, Lisset G Neri-García, Oscar E Romero-González, Joshua A Terrones-Cruz, Laura C García-Carnero,* Héctor M Mora-Montes* Departamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de ...
Nava-Pérez N   +5 more
doaj  

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