Severe Sporotrichosis Caused by Sporothrix brasiliensis: Antifungal Susceptibility and Clinical Outcomes [PDF]
Itraconazole is the first choice for treating sporotrichosis. Amphotericin B is indicated for severe and disseminated forms. The aim of the study was to evaluate the antifungal susceptibility of Sporothrix brasiliensis strains isolated from patients with severe sporotrichosis treated with amphotericin B and correlate with clinical outcomes.
Fichman V +5 more
europepmc +4 more sources
Skin Mast Cells Contribute to Sporothrix schenckii Infection [PDF]
Background: Sporothrix schenckii (S. schenckii), a dimorphic fungus, causes sporotrichosis. Mast cells (MCs) have been described to be involved in skin fungal infections. The role of MCs in cutaneous sporotrichosis remains largely unknown. Objectives:
Frischbutter, Stefan +8 more
core +1 more source
Differential Recognition of Clinically Relevant Sporothrix Species by Human Granulocytes
Sporotrichosis is a cutaneous mycosis that affects humans and animals and has a worldwide distribution. This infection is mainly caused by Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa.
Ana K. Galván-Hernández +4 more
doaj +1 more source
An anti-adhesive peptide found in extracellular vesicles from <i>Sporothrix brasiliensis</i> and <i>Sporothrix schenckii</i>. [PDF]
de Souza CM +10 more
europepmc +2 more sources
CRISPR-based tools for targeted genetic manipulation in pathogenic Sporothrix species
Sporothrix brasiliensis is an emerging fungal pathogen frequently associated with zoonotic transmission of sporotrichosis by contaminated cats. Within 25 years, the disease has spread not only throughout Brazil but now to neighboring countries in Latin ...
Remi Hatinguais +5 more
doaj +1 more source
In vitro evaluation of Sporothrix brasiliensis biotherapic
Background: Sporothrix brasiliensis is one of the most virulent zoonosis which affects animals and humans. This fungus is responsible for subcutaneous infection and its contamination is possible through trauma to the skin. Sporotrichosis is highly prevalent in feline. And Rio de Janeiro appears to have the highest occurrence of cases.
Gleyce Moreno Barbosa +3 more
openaire +1 more source
Evaluation of T3B fingerprinting for identification of clinical and environmental Sporothrix species [PDF]
In this study, PCR fingerprinting using the universal primer T3B was applied to distinguish among clinical and environmental species of the Sporothrix complex, Sporothrix brasiliensis, S. globosa, S. mexicana, S. pallida, S. luriei and S. schenckii sensu
Arrillaga-Moncrieff +39 more
core +1 more source
Multicenter, International Study of MIC/ MEC Distributions for definition of epidemiological cutoff values for sporothrix species identified by molecular methods [PDF]
Clinical and Laboratory Standards Institute (CLSI) conditions for testing the susceptibilities of pathogenic Sporothrix species to antifungal agents are based on a collaborative study that evaluated five clinically relevant isolates of Sporothrix ...
Abreu, D.P.B. +20 more
core +1 more source
Sporothrix brasiliensis is the prevalent agent of a large zoonotic outbreak in Brazil. With the involvement of several thousands of cases, this is the largest cohort of human and animal sporotrichosis on record in the world.
Luana Rossato +6 more
doaj +1 more source
Differential Recognition of Clinically Relevant Sporothrix Species by Human Mononuclear Cells
Sporotrichosis is a human and animal fungal infection distributed worldwide that is caused by the thermodimorphic species of the Sporothrix pathogenic clade, which includes Sporothrix brasiliensis, Sporothrix schenckii, and Sporothrix globosa.
Laura C. García-Carnero +3 more
doaj +1 more source

