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2012
Sporozoites, the stage of Plasmodium infectious to vertebrates when injected in the skin by a mosquito vector, are highly motile cells. Their unusual form of gliding motility is essential for infectivity, allowing the parasite to travel through both the mosquito and mammalian hosts, invading different cell types and escaping immune cell-mediated death.
Allison F, Carey +2 more
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Sporozoites, the stage of Plasmodium infectious to vertebrates when injected in the skin by a mosquito vector, are highly motile cells. Their unusual form of gliding motility is essential for infectivity, allowing the parasite to travel through both the mosquito and mammalian hosts, invading different cell types and escaping immune cell-mediated death.
Allison F, Carey +2 more
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Gram Staining of Pneumocystis Sporozoites
Annals of Internal Medicine, 1984Excerpt To the editor: Recently, Macher and coworkers (1) have described the usefulness of gram-staining touch preparations of lung biopsy material for the diagnosis ofPneumocystis cariniipneumonia...
J A, Rankin, K R, Young
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Implications of imaging malaria sporozoites
Trends in Parasitology, 2008The sporozoites of Plasmodium parasites undergo several transmigrations before their establishment in the hepatocytes of a vertebrate host. Techniques that illustrate parasite intra-vital migration and their interaction with host cells will advance the understanding of parasite biology. In a recent publication, Amino et al. provided a detailed protocol
Qijun, Chen, Heng, Wang
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Malaria sporozoite: migrating for a living
Trends in Molecular Medicine, 2004Plasmodium sporozoite invasion of host hepatocytes is an initial key step in infection by malaria parasite. Sporozoites can enter hepatocytes via two distinct pathways: by disruption of the plasma membrane followed by parasite migration through cells, or by the formation of a vacuole essential for further differentiation of the parasite. For Plasmodium
Olivier, Silvie +3 more
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Theileria annulata sporozoite targets
Parasite Immunology, 1994SUMMARYBovine peripheral blood mononuclear cells (PBM) infected in vitro with Theileria annulata sporozoites have previously been characterized as MHC class II+ mature macrophages. The ability of T. annulata sporozoites to infect different subpopulations of MHC class II+ bovine monocytes was investigated.
J D, Campbell +4 more
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Freezing Excysted Coccidial Sporozoites
The Journal of Parasitology, 1969Excysted sporozoites of Eimeria adenoeides, E. mivati, and E. tenella were placed in media containing different concentrations (2.5, 5, 7.5, 10, 12.5, and 15%) of dimethyl sulfoxide (DMSO). In the absence of freezing, survival of sporozoites was better at the lower concentrations.
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Multistep adhesion of Plasmodium sporozoites
The FASEB Journal, 2010Adhesion of eukaryotic cells is a complex process during which interactions between extracellular ligands and cellular receptors on the plasma membrane modulate the organization of the cytoskeleton. Pathogens particularly rely often on adhesion to tissues or host cells in order to establish an infection.
Hegge, S. +6 more
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Experimental Parasitology, 1993
Irradiated sporozoites are generally thought to elicit protective immune responses that are parasite stage and species specific. But immunization with Plasmodium falciparum sporozoites delivered by the bite of infected mosquitoes protects an average of 60% mice from Plasmodium berghei sporozoite infection.
B J, Sina +4 more
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Irradiated sporozoites are generally thought to elicit protective immune responses that are parasite stage and species specific. But immunization with Plasmodium falciparum sporozoites delivered by the bite of infected mosquitoes protects an average of 60% mice from Plasmodium berghei sporozoite infection.
B J, Sina +4 more
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Excystment by sporozoites of malaria parasites
Nature, 1974IT IS widely assumed that the mature oocyst of the malaria parasite bursts and liberates the sporozoites en masse1 although studies on the intestinal coccidians have clearly shown that the sporozoites escape through the wall of the sporocyst, a structure analagous to the oocyst of malaria parasites, by way of specialised pores2–4.
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Cell invasion by Theileria sporozoites
Trends in Parasitology, 2003Abstract Theileria are intracellular protozoan parasites of veterinary importance, and their impact on livestock production in many developing countries has a significant negative effect on the quality of human life. Host cell invasion is a crucial aspect of Theileria biology.
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