Results 91 to 100 of about 982,890 (288)

A lesson learned in time: Advice shared by experienced sport psychologists [PDF]

open access: yes, 2015
Through experience, sport psychologists will learn countless valuable lessons. Some lessons, however, are likely to stand out vividly to a psychologist because they made a valuable difference to how they practise.
McCormick, Alister, Meijen, Carla
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Electronic sport and its impact on future sport

open access: yes, 2010
The mere mentioning of computer gaming (E-sport) as a form of sport i subversive, according to public health and media discourses. As a matter of fact, the two practices are considered to be oppositional.
Jonasson, Kalle,   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Sports Activity and Smoking, Alcohol and Drug Abuse among Students

open access: yesAnnals of Applied Sport Science, 2018
Background. Despite the research being accomplished so far, there is no clear answer to the question that "Does sports help to prevent and reducing the abuse of drug, alcohol, and smoking in young people as it believed in public". Objective(s).
Somayeh Ahmadabadi
doaj  

Sports and Leasure Activities of Students at the University of Dorpat (Yuryev) (1802–1917)

open access: yesКиївські історичні студії
The article is devoted to the study of sports and leisure activities of students at the University of Dorpat in 1802–1917. The conquest of the former Swedish lands by the Russian Empire led to the growing dissatisfaction among the youth of the Livonian ...
Nataliia Sokolova   +2 more
doaj   +1 more source

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