Results 91 to 100 of about 455,143 (313)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Sports Activity and Smoking, Alcohol and Drug Abuse among Students
Annals of Applied Sport Science, 2018 Background. Despite the research being accomplished so far, there is no clear answer to the question that "Does sports help to prevent and reducing the abuse of drug, alcohol, and smoking in young people as it believed in public". Objective(s).
Somayeh Ahmadabadi
doaj
‘We are rolling and vaulting tonight’: sport programmes, urban regeneration and the politics of parkour in Turin, Italy [PDF]
, 2017 Nicola De Martini Ugolotti
openalex +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source