Results 101 to 110 of about 982,890 (288)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Sports and physical activity of Poles in the context of good health and well-being as a sustainable development goal

Baltic Journal of Health and Physical Activity
Investing in physical activity (PA) is vital for achieving sustainable development goals. We examine PA trends in Poland using data from Eurobarometer surveys conducted in 2013, 2017, and 2022.
Elżbieta BIERNAT, Monika PIĄTKOWSKA, Robert PODSTAWSKI   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Overview Report - Think Tank 2: Sport Mega-Event Impacts, Leveraging, and Legacies

, 2011
On November 11-12, 2011 the UBC Centre for Sport and Sustainability held its second think tank on the topic of Sport Mega-Event Impacts, Leveraging, and Legacies.
Centre for Sport and Sustainability
core   +1 more source

Gross Motor Performance, Participation and Quality of Life After Adapted Physical Activity Interventions in Pediatric Populations with Neuromotor Disability: A Systematic Review

Children
Background/Objectives: Physical activity is generally recommended, but youth with disabilities present increased sedentary behaviors. This is often due to limited or inaccessible exercise options.
Silvia Faccioli, Avola Marianna, Mangano Giulia Rita Agata, Sghedoni Silvia, Sassi Silvia   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A sport-for-protection program reduces suicidal ideation in youth affected by displacement: a secondary analysis of the Game Connect trial in Uganda

Frontiers in Psychiatry
IntroductionDisplaced youth face numerous stressors and are at high risk of experiencing suicidal ideation. Sport-for-protection programs offer a potentially effective strategy to reduce this risk; however, randomized controlled trials (RCTs) evaluating ...
Kathleen Latimer, Rita Larok, Rita Larok, John Paul Nyeko, Bashir Lukungu, Simon Rosenbaum, Simon Rosenbaum, Lydia Murungi, Robinah Nannungi, Jeroen Carrin, Esther Nanfuka Kalule, Ronald Luwangula, Davy Vancampfort, Davy Vancampfort, Davy Vancampfort   +14 more
doaj   +1 more source

Proposal to Sports Pharmacist as a Sports Doctor

YAKUGAKU ZASSHI, 2011
I am a team doctor of three competition groups including professional cycling team for ten years. The most troublesome issue as a sports doctor is the problem about doping. I cope thanks to a mobile telephone and an e-mail regardless of place and time, but introduce some examples because I still experience many doping "near miss" cases.
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Back Matter

Journal Sport Area, 2020
sport
doaj   +2 more sources