Results 41 to 50 of about 8,457 (238)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Evaluation of the relationship of the climbing level of sport climbers with selected anthropometric indicators and diet composition

Central European Journal of Sport Sciences and Medicine, 2019
Climbing is becoming more and more popular. During 2020 Olympic Games this discipline will be competed for the first time. Individualized diet plays a significant role among representatives of all sport disciplines.
Anna Przeliorz-Pyszczek, Katarzyna Gołąbek, Bożena Regulska-Ilow   +2 more
doaj   +1 more source

The Estimation of Critical Angle in Climbing as a Measure of Maximal Metabolic Steady State

Frontiers in Physiology, 2022
Purpose: Sport climbing is a technical, self-paced sport, and the workload is highly variable and mainly localized to the forearm flexors. It has not proved effective to control intensity using measures typical of other sports, such as gas exchange ...
Jiří Baláš, Jan Gajdošík, David Giles, Simon Fryer   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The Effects of Therapeutic Climbing on Pain, Function, and Muscle Thickness of the Supraspinatus and Infraspinatus in Sport Climbers with Shoulder Pain: A Randomized Controlled Trial

Applied Sciences
This study investigated the effects of therapeutic climbing on pain, function, and rotator cuff muscle thickness in sport climbers with shoulder pain using a prospective, single-blind randomized controlled trial design.
Geonwoo Sim, Chunghyun Son, Sangcheol Im, Kyoung Kim   +3 more
doaj   +1 more source

Analysis of Competition and Training Videos of Speed Climbing Athletes Using Feature and Human Body Keypoint Detection Algorithms

Sensors, 2022
Compared to 25 years ago, the climbing sport itself has changed dramatically. From a rock climbing modification to a separation in three independent disciplines, the requirements to athletes and trainers increased rapidly.
Dominik Pandurevic, Paweł Draga, Alexander Sutor, Klaus Hochradel   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Anthropometric Parameters and Body Composition in Elite Lead Climbers and Boulderers—A Retrospective Study

Applied Sciences
Based on previous research studies and systematic reviews, success in sport climbing seems to be determined by variables such as strength, power, or endurance.
Agata Ginszt, Grzegorz Zieliński, Aleksandra Dolina, Estera Stachyra, Monika Zaborek-Łyczba, Jakub Łyczba, Piotr Gawda, Michał Ginszt   +7 more
doaj   +1 more source

Climbing crags recommender system in Arco, Italy: a comparative study

Frontiers in Big Data, 2023
Outdoor sport climbing is popular in Northern Italy due to its vast amount of rock climbing places (such as crags). New climbing crags appear yearly, creating an information overload problem for tourists who plan their sport climbing vacation ...
Iustina Ivanova, Mike Wald
doaj   +1 more source