Results 51 to 60 of about 97,656 (288)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Climbing is becoming more and more popular. During 2020 Olympic Games this discipline will be competed for the first time. Individualized diet plays a significant role among representatives of all sport disciplines.
Anna Przeliorz-Pyszczek +2 more
doaj +1 more source
The Bolton Dome Fundraiser Film Thesis [PDF]
The sport of rock climbing has evolved drastically since its conception, nearly 150 years ago. Recently, climbing has experienced a surge in popularity and has begun to leave noticeable impacts on fragile cliffside ecosystems.
query, fraser
core +1 more source
The (re)production of climbing space: bodies, gestures, texts [PDF]
According to Lefebvre, space is not an absolute given, an empty and presumed starting point, but space is produced through human action. Further, he contends, there is a material basis to the production of space – the “practical and fleshy body”.
Rickly, J.M.
core +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Estimation of Critical Angle in Climbing as a Measure of Maximal Metabolic Steady State
Purpose: Sport climbing is a technical, self-paced sport, and the workload is highly variable and mainly localized to the forearm flexors. It has not proved effective to control intensity using measures typical of other sports, such as gas exchange ...
Jiří Baláš +3 more
doaj +1 more source
Analisis Implementasi Standar Keselamatan dan Pemakaian Peralatan Panjat Tebing untuk Meningkatkan Keselamatan Kerja pada Kegiatan Sport Climbing (Studi pada Fpti Jawa Tengah) [PDF]
Broadly speaking, the climbing wall is divided into two: Climbing Natural and Artificial Climbing. Artificial Climbing identical with Sport Climbing or Climbing Achievement commandeered By FPTI (Indonesian Rock Climbing Federation).
Jayanti, M.Sc, dr. Siswi +2 more
core
Exploring efficacy in personal constraint negotiation: an ethnography of mountaineering tourists [PDF]
Limited work has explored the relationship between efficacy and personal constraint negotiation for adventure tourists, yet efficacy is pivotal to successful activity participation as it influences people’s perceived ability to cope with constraints, and
Adele Doran +9 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

