Results 51 to 60 of about 97,656 (288)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Evaluation of the relationship of the climbing level of sport climbers with selected anthropometric indicators and diet composition

open access: yesCentral European Journal of Sport Sciences and Medicine, 2019
Climbing is becoming more and more popular. During 2020 Olympic Games this discipline will be competed for the first time. Individualized diet plays a significant role among representatives of all sport disciplines.
Anna Przeliorz-Pyszczek   +2 more
doaj   +1 more source

The Bolton Dome Fundraiser Film Thesis [PDF]

open access: yes, 2018
The sport of rock climbing has evolved drastically since its conception, nearly 150 years ago. Recently, climbing has experienced a surge in popularity and has begun to leave noticeable impacts on fragile cliffside ecosystems.
query, fraser
core   +1 more source

The (re)production of climbing space: bodies, gestures, texts [PDF]

open access: yes, 2016
According to Lefebvre, space is not an absolute given, an empty and presumed starting point, but space is produced through human action. Further, he contends, there is a material basis to the production of space – the “practical and fleshy body”.
Rickly, J.M.
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Estimation of Critical Angle in Climbing as a Measure of Maximal Metabolic Steady State

open access: yesFrontiers in Physiology, 2022
Purpose: Sport climbing is a technical, self-paced sport, and the workload is highly variable and mainly localized to the forearm flexors. It has not proved effective to control intensity using measures typical of other sports, such as gas exchange ...
Jiří Baláš   +3 more
doaj   +1 more source

Analisis Implementasi Standar Keselamatan dan Pemakaian Peralatan Panjat Tebing untuk Meningkatkan Keselamatan Kerja pada Kegiatan Sport Climbing (Studi pada Fpti Jawa Tengah) [PDF]

open access: yes, 2013
Broadly speaking, the climbing wall is divided into two: Climbing Natural and Artificial Climbing. Artificial Climbing identical with Sport Climbing or Climbing Achievement commandeered By FPTI (Indonesian Rock Climbing Federation).
Jayanti, M.Sc, dr. Siswi   +2 more
core  

Exploring efficacy in personal constraint negotiation: an ethnography of mountaineering tourists [PDF]

open access: yes, 2019
Limited work has explored the relationship between efficacy and personal constraint negotiation for adventure tourists, yet efficacy is pivotal to successful activity participation as it influences people’s perceived ability to cope with constraints, and
Adele Doran   +9 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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