Results 61 to 70 of about 1,583,335 (284)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Reconsidering feminisms and the work of Norbert Elias for understanding gender, sport and sport-related activities [PDF]
, 2008 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 North West Counties Physical Education Association and SAGE Publications.This paper reconsiders the relationships between feminist ...
Mansfield, L, Mansfield, L.
core +1 more source
Frontiers in Human DynamicsThis paper presents research conducted in an informal settlement in Paarl, Western Cape (South Africa). The research demonstrates the importance of team sport activities as an instrument to encourage community cohesion.
Anele Horn, Willis Marais
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The role of sport in advancing environmental sustainability: A case study of community-level hockey facilities in Ontario, Canada [PDF]
, 2020 Environmental sustainability (ES) in sport represents an emerging area of research that is gaining popularity worldwide. While this is encouraging, the gap between sport and the environment needs to be further explored.
Kelly, Nolan
core
Prevalence of sexual harassment among Norwegian female elite athletes in relation to sport type [PDF]
, 2004 Although it is often assumed that the prevalence of sexual harassment is different in different sports, this assumption has not been empirically tested. This study considers whether the experience of sexual harassment varies by sport.
Sundgot-Borgen, J +2 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
American Professional Sport Facilities: Considerations for the Future [PDF]
This work reveals American professional sport facilities impose staggering financial and spatial costs on the surrounding communities and suggests three areas future professional sport facility designers should consider before partaking in future ...
Dave Shonk, Chad Seifried
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Development and promotion strategies of pickleball in Jambi Province
Sriwijaya Journal of SportResearch Problems: Challenges such as limited facilities and the small number of active players are obstacles faced by the community in popularising this sport.
Nurhaliza Nurhaliza +2 more
doaj +1 more source