Results 81 to 90 of about 388,709 (308)

Development and promotion strategies of pickleball in Jambi Province

open access: yesSriwijaya Journal of Sport
Research Problems: Challenges such as limited facilities and the small number of active players are obstacles faced by the community in popularising this sport.
Nurhaliza Nurhaliza   +2 more
doaj   +1 more source

State of Play in Western New York: Analysis and Recommendations [PDF]

open access: yes, 2017
This report offers an independent assessment of the state of play for kids and sports in the eight-county region comprising Western New York-Allegany, Cattaraugus, Chautauqua, Erie, Genesee, Niagara, Orleans, and Wyoming counties.
Aspen Institute Sports & Society Program   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

American Professional Sport Facilities: Considerations for the Future [PDF]

open access: yes
This work reveals American professional sport facilities impose staggering financial and spatial costs on the surrounding communities and suggests three areas future professional sport facility designers should consider before partaking in future ...
Chad Seifried, Dave Shonk
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Constructing sports facilities using environment-friendly materials

open access: yesFrontiers in Materials
This study is focused on applying environment-friendly materials (EFM) to construct sports facilities for sustainability. The current status and future potential of using EFM in sports facility construction are concretely discussed with a thorough ...
Rui Li, Chenxi Zhai
doaj   +1 more source

Perancangan Interior Sekolah Bola Basket Archo Di Surabaya [PDF]

open access: yes, 2014
Surabaya, who received the title as a warehouse in East Java and National athlete, became one barometer sport in Indonesia, one of the sport of basketball.
Santosa, D. Y. (Denny)
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Families’ and children’s experience of sport and informal activity in Olympic areas of the East End. [PDF]

open access: yes
Sport England is interested to know how families with children experience the following aspects of neighbourhood life: involvement in sport; access to facilities; activities for young people; and the engagement of young people in poor areas in the ...
Davidson, Rosemary, Power, Anne
core   +1 more source

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