Results 121 to 130 of about 2,685,797 (335)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The Effect of Perceptual-Cognitive Skills in College Elite Athletes: An Analysis of Differences Across Competitive Levels

open access: yesSports
Background: Athletes with expertise in sports show extensive procedural and factual information, enhancing their ability to focus attention, use cues, and anticipate events.
Kuo-Cheng Wu   +6 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Psychiatry and Sports Medicine

open access: yesDeutsche Zeitschrift für Sportmedizin, 2021
Scherr J, Claussen MC
doaj   +1 more source

Monitoring and Improving Sleep Quality in Professional Athletes

open access: yesQuality in Sport
Introduction and Purpose: Sleep is a fundamental component of performance, recovery, and overall health in professional athletes. However, sleep disturbances—including insufficient duration, poor quality, and insomnia—are highly prevalent in this ...
Marcelina Guzik   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

"This is the best game!"

open access: yesEludamos
This article analyses The Best Game, a fictional arcade game encountered in the YouTube animated series Bee and PuppyCat. Although arcade games in North America have long been conceptualised as sites of masculine skill-based competition and mastery ...
Jacqueline Moran
doaj   +1 more source

Inducements of Rochester Americans Fans [PDF]

open access: yes, 2017
The purpose of this research was to examine the factors that motivate minor league sports fans. Specifically, this research was designed to analyze the factors that influence a fan’s motivation to attend Rochester Americans games.
D\u27Agostino, Alex
core   +1 more source

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