Results 81 to 90 of about 565,621 (377)
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu+20 more
wiley +1 more source
Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]
Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M.+5 more
core +1 more source
Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich+20 more
wiley +1 more source
Novel Spotted Fever Group Rickettsiosis, Brazil
We report a clinical case of spotted fever group rickettsiosis acquired in São Paulo, Brazil. Definitive diagnosis was supported by seroconversion between acute-phase and convalescent-phase serum samples.
Mariana G. Spolidorio+5 more
doaj +1 more source
Japanese Spotted Fever in Eastern China, 2013
We isolated Rickettsia japonica from a febrile patient in Lu’an City, China, in 2013. Subsequently, we found an R. japonica seroprevalence of 54.8% (494/902) in the rural population of Anhui Province and an R.
Jiabin Li+14 more
semanticscholar +1 more source
Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease - United States. [PDF]
The term "chronic Lyme disease" is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2).
Blackburn, Brian G+9 more
core +1 more source
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson+8 more
wiley +1 more source
This paper reports the first isolation of a spotted fever group rickettsia from an Amblyomma cooperi ixodid collected from a capybara (Hydrochaeris hydrochaeris) in an endemic area of spotted fever in the County of Pedreira, State of São Paulo, Brazil ...
Elba Regina Sampaio de Lemos+7 more
doaj +1 more source
A contribution to a knowledge of Canadian ticks [PDF]
During recent years our knowledge of the biology and distribution of the ticks has greatly increased owing to the discovery of the economic importance of this group as carriers of certain serious diseases to man and domesticated animals. In North America
Hewitt, Charles Gordon
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