Results 111 to 120 of about 471,278 (247)

A novel Osteoarthritis scoring system to separate typical OA joint degeneration from non-typical lesions in male Sprague Dawley rats

Osteoarthritis and Cartilage Open
Objective: To develop a novel scoring system to characterize osteoarthritis-related degeneration distinct from spontaneous subchondral bone lesions observed in the tibia and femur of male Sprague Dawley rats.
Nada Abughazaleh, Ruth-Anne Seerattan, David A. Hart, Raylene A. Reimer, Walter Herzog   +4 more
doaj   +1 more source

In-vivo experimental model for silicosis : fisher 344, sprague dawley and wistar rat strains [PDF]

, 1993
The selection of an experimental model for silicosis requires a thorough understanding of a number of different pulmonary parameters specific to the animal that is to be used (e.g., clearance time, penetration curves, anatomical differences...), and of ...
Honnons, Sylvie, Oberson, Dominique, Porcher, Jean-Marc   +2 more
core   +1 more source

Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals [PDF]

, 2017
Acknowledgements This study was partially supported by grants from the Seed Funding Programme for Basic Research (Project Number 201211159146 and 201411159213), the University of Hong Kong.
Cheung, H. P., Chung, F. W. S., Lao, L. X., Ng, T. B., Sze, S. C. W., Tong, Y., Wang, S. W., Zhang, Y. B., Zhang, Z. J.   +8 more
core   +1 more source

Chordoma in a Sprague-Dawley Rat [PDF]

Toxicologic Pathology, 1991
G M, Zwicker, R C, Eyster
openaire   +2 more sources

Spontaneous Cardiomyopathy in Young Sprague-Dawley Rats

Toxicologic pathology (Print), 2013
Cardiovascular safety signals in nonclinical studies remain among the main reasons for drug attrition during pharmaceutical research and development. Drug-induced changes can be functional and/or associated with morphological alterations in the normal ...
F. Chanut, Carie L. Kimbrough, R. Hailey, B. Berridge, Angela Hughes-Earle, Rhiannon Davies, Kimberly Roland, Alan H. Stokes, A. Casartelli, M. York, H. Jordan, F. Crivellente, P. Cristofori, Heath C. Thomas, J. Klapwijk, R. Adler   +15 more
semanticscholar   +1 more source

Effect of 3β, hydroxy-lup-20(29)-en-28-oic acid on 7,12-Dimethylbenz(a) anthracene impaired cellular homeostasis in extrahepatic organs of Sprague Dawley rats

Journal of Xenobiotics, 2017
3β, hydroxy-lup-20(29)-en-28-oic acid (Betulinic acid), a pentacyclic lupane-type triterpene has diverse pharmacological functions both in vitro and in vivo.
Pardeep Kaur, Rajbir Kaur, Rohit Arora, Saroj Arora   +3 more
doaj   +1 more source

Hypolipidemic Effect of Extra Virgin Olive Oil in Diabetic Rats

Journal of Rawalpindi Medical College, 2012
Background: To evaluate the effect of monounsaturated fatty acid and phenolic compounds enriched extra virgin olive oil on correction of dyslipidemia in diabetic rats.
Muhammad Javad Yousaf
doaj  

Metastability of Neuronal Dynamics during General Anesthesia: Time for a Change in Our Assumptions?

Frontiers in Neural Circuits, 2017
There is strong evidence that anesthetics have stereotypical effects on brain state, so that a given anesthetic appears to have a signature in the electroencephalogram (EEG), which may vary with dose.
Andrew E. Hudson
doaj   +1 more source

Subchronic Hepatotoxicity Evaluation of 2,3,4,6-Tetrachlorophenol in Sprague Dawley Rats

Journal of Toxicology, 2012
Male Sprague Dawley rats were exposed to 2,3,4,6-tetrachlorophenol (TCP) for 5 days, 2 weeks, 4 weeks, or 13 weeks. TCP was administered by gavage at doses of 0, 10, 25, 50, 100, or 200 mg/kg/day.
Darol E. Dodd, Linda J. Pluta, Mark A. Sochaski, Deborah A. Banas, Russell S. Thomas   +4 more
doaj   +1 more source

Polyorchidism in a young Sprague-Dawley rat

Journal of Toxicologic Pathology
Duplicate testes lined in series were observed in the right scrotum of a 6-week-old Sprague-Dawley rat in a single-dose toxicity study. Of the two right testicles, one was spherical and less than half the size of a normal testis. The other was oval-shaped, slightly smaller than a normal testis, and possessed clear, tortuous blood vessels similar to ...
Obara, Ryo D., Kato, Yuki, Asaoka, Yoshiji, Fujisawa, Kae, Kashiwagi, Emi, Koyama, Kenji, Mukai, Miho, Tajiri, Minako, Torii, Mikinori   +8 more
openaire   +2 more sources