Results 11 to 20 of about 330,960 (360)

Voluntary Alcohol Intake following Blast Exposure in a Rat Model of Mild Traumatic Brain Injury. [PDF]

open access: yesPLoS ONE, 2015
Alcoholism is a frequent comorbidity following mild traumatic brain injury (mTBI), even in patients without a previous history of alcohol dependence. Despite this correlational relationship, the extent to which the neurological effects of mTBI contribute
Yi Wei Lim   +5 more
doaj   +1 more source

Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats

open access: yesParticle and Fibre Toxicology, 2020
Background Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive.
Astrid Skovmand   +12 more
doaj   +1 more source

Effect of foxtail millet supplementation in comparison to atorvastatin on high-fat diet-induced hyperlipidemia in rats

open access: yesAsian Journal of Medical Sciences, 2023
Background: Hyperlipidemia can be defined as an increased concentration of lipids in the blood. Foxtail millet (FTM) is a nutrient-rich cereal containing several phytochemicals which have possible lipid-lowering and glucose-lowering abilities ...
Praneeth Reddy Onteddu   +4 more
doaj   +1 more source

Acute oral toxicity of zein nanoparticles with encapsulated gamma oryzanol in Sprague Dawley rats [PDF]

open access: yesE3S Web of Conferences, 2021
Gamma oryzanol (GO) is well known for its antioxidant activity and health-promoting benefits. The gamma oryzanol-loaded zein nanoparticles (GOZNs) were successfully prepared in our previous study. In the present work, the acute oral toxicity of GOZNs was
Rodsuwan Ubonphan   +6 more
doaj   +1 more source

Systemic candidiasis in Sprague-Dawley rats [PDF]

open access: yesMedical Mycology, 1996
A reproducible model of a generalized Candida albicans infection was established in rats to allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the intravenous C. albicans model in mice, which serves as a primary model for in vivo efficacy studies of antimycotic compounds, the infectious process in Sprague-Dawley rats is ...
openaire   +2 more sources

Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague–Dawley rats

open access: yesDiabetology & Metabolic Syndrome, 2018
BackgroundIn humans and animal models, excessive intake of dietary fat, fructose and cholesterol has been linked to the development of non-alcoholic fatty liver disease (NAFLD). However, the individual roles of the dietary components remain unclear.
V. Jensen   +7 more
semanticscholar   +1 more source

Urolithiasis in the Sprague-Dawley rat [PDF]

open access: yesLaboratory Animals, 1979
A 7 year collection of calculi from short- and long-term studies with Sprague-Dawley rats showed that although the incidence of rats with urolithiasis was small (0·5%), the variety of sizes and composition of the calculi could be of general interest.
openaire   +2 more sources

Spontaneous Iron Overload in Sprague-Dawley Rats [PDF]

open access: yesToxicologic Pathology, 1997
In a review of the toxicological studies performed in our laboratory during the period 1986-1995, we occasionally observed significant iron overloading in the liver. Liver tissue was examined by light and electron microscopy, and the results were analyzed by sex and age (7, 9, 11, 19, 31, 59, and 111 wk).
R, Masson, N O, Roome
openaire   +2 more sources

Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies

open access: yesbioRxiv, 2018
Sprague Dawley (SD) rats are among the most widely used outbred laboratory rat populations. Despite this, the genetic characteristics of SD rats have not been clearly described, and SD rats are rarely used for experiments aimed at exploring genotype ...
A. Gileta   +12 more
semanticscholar   +1 more source

Effects of Repeated Lipopolysaccharide Treatment on Growth Performance, Immune Organ Index, and Blood Parameters of Sprague-Dawley Rats

open access: yesJournal of Veterinary Research, 2018
Introduction The study was designed to investigate the effects of repeated lipopolysaccharide (LPS) treatment on growth performance, lymphoid organ indexes, and blood cells in Sprague-Dawley rats.
Youbao Zhong   +3 more
semanticscholar   +1 more source

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