Results 21 to 30 of about 908,946 (295)
Keishibukuryogan is not carcinogenic in Sprague-Dawley rats
Journal of Toxicologic Pathology, 2016 Keishibukuryogan is a traditional Japanese medicine widely administered to patients with menopausal symptoms. Because humans use it on a long-term basis, we believed that a carcinogenicity study was warranted. We orally administered keishibukuryogan (TJ-25) extract powder to 6-week-old Sprague-Dawley rats [Crl:CD(SD)], which were divided into four ...
Kanitani, Masanao +3 more
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Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats
, 2020 Let alone calorie restriction, life span extension in higher organisms has proven to be difficult to achieve using simple drugs. Previous studies have shown that the polyamine spermidine increased the maximum life span in C.
Popa-Wagner, A +6 more
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Spontaneous Teratoma in a Sprague-Dawley Rat
Experimental Animals, 1985 An 6-week-old male Sprague-Dawley rat which had undergone no experimental treatment died from enlargement of the abdomen. At necropsy, a spherical mass measuring about 3 X 4cm in diameter was connected to the retroperitoneal region cross to the middorsal line of the body.
T, Itoh, K, Shirota, N, Kagiyama
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Fatty acid synthase and adipsin mRNA levels in obese and lean JCR:LA-cp rats: effect of diet.
Journal of Lipid Research, 1992 In Sprague-Dawley rats, fatty acid synthase (FAS) activity is suppressed by dietary fat. To test the hypothesis that a defect in regulation of de novo fatty acid synthesis exists in massive obesity, we investigated the effect of diet on FAS mRNA levels ...
G Shillabeer +5 more
doaj +1 more source
Effect of Pomegranate Extract (Punica Granatum L) on Pulmonary Arterial Pressure in Sprague Dawley Rat with Pulmonary Arterial Hypertension [PDF]
, 2020 Congenital heart disease causes pulmonary arterial hypertension, heart failure, and early death. Pulmonary arterial hypertension causes pulmonary arterial wall remodeling, inflammation, deposition of extracellular matrix protein, collagen synthesis, and ...
Taufiq Hidayat, - +2 more
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Ovarian Neoplasia in the Sprague-Dawley Rat [PDF]
Environmental Health Perspectives, 1987 Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor,
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Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the chronic stress induced decline in plasma Neuropeptide Y (NPY) level and protective effects of Alpha Tocopherol (AT) on maintenance of Neuropeptide Y level. Study Design: Quasi-experimental study.
Saadia Zainab +3 more
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Systemic candidiasis in Sprague-Dawley rats [PDF]
Medical Mycology, 1996 A reproducible model of a generalized Candida albicans infection was established in rats to allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the intravenous C. albicans model in mice, which serves as a primary model for in vivo efficacy studies of antimycotic compounds, the infectious process in Sprague-Dawley rats is ...
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Use Of The Prebiotic Inulin In The Prevention Of Adverse Signs Of Acute Colitis
Acta Veterinaria, 2015 The aim of this study was to investigate the influence of prebiotic inulin diet intervention on the activity of β-glucuronidase and counts of coliforms and lactobacilli in fresh caecal digesta, cytokine levels (IL-6, IL-8) and transcription nuclear ...
Emília Hijová +5 more
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Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats
Toxicology Reports, 2020 Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan +9 more
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