Results 11 to 20 of about 247,912 (307)

Olfactory Bulbectomy Model of Depression Lowers Responding for Food in Male and Female Rats: The Modulating Role of Caloric Restriction and Response Requirement

open access: yesBiomedicines, 2023
Depression is a psychiatric disorder characterized by a marked decrease in reward sensitivity. By using the olfactory bulbectomy (OBX) model of depression, it was shown that OBX rats display enhanced drug-taking and seeking behaviors in a self ...
Liana Fattore   +3 more
doaj   +1 more source

Voluntary Alcohol Intake following Blast Exposure in a Rat Model of Mild Traumatic Brain Injury. [PDF]

open access: yesPLoS ONE, 2015
Alcoholism is a frequent comorbidity following mild traumatic brain injury (mTBI), even in patients without a previous history of alcohol dependence. Despite this correlational relationship, the extent to which the neurological effects of mTBI contribute
Yi Wei Lim   +5 more
doaj   +1 more source

Effect of foxtail millet supplementation in comparison to atorvastatin on high-fat diet-induced hyperlipidemia in rats

open access: yesAsian Journal of Medical Sciences, 2023
Background: Hyperlipidemia can be defined as an increased concentration of lipids in the blood. Foxtail millet (FTM) is a nutrient-rich cereal containing several phytochemicals which have possible lipid-lowering and glucose-lowering abilities ...
Praneeth Reddy Onteddu   +4 more
doaj   +1 more source

Acute oral toxicity of zein nanoparticles with encapsulated gamma oryzanol in Sprague Dawley rats [PDF]

open access: yesE3S Web of Conferences, 2021
Gamma oryzanol (GO) is well known for its antioxidant activity and health-promoting benefits. The gamma oryzanol-loaded zein nanoparticles (GOZNs) were successfully prepared in our previous study. In the present work, the acute oral toxicity of GOZNs was
Rodsuwan Ubonphan   +6 more
doaj   +1 more source

Urolithiasis in the Sprague-Dawley rat [PDF]

open access: yesLaboratory Animals, 1979
A 7 year collection of calculi from short- and long-term studies with Sprague-Dawley rats showed that although the incidence of rats with urolithiasis was small (0·5%), the variety of sizes and composition of the calculi could be of general interest.
openaire   +2 more sources

Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats

open access: yesParticle and Fibre Toxicology, 2020
Background Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive.
Astrid Skovmand   +12 more
doaj   +1 more source

Hematoxicity of amodiaquine in sprague-dawley rats

open access: yesToxicology International, 2012
The use of amodiaquine (AQ) and its associated toxic effect has been a major public health concern since cases of life-threatening agranulocytosis and hepatic toxicity were reported during its prophylactic use. The objective of this study was to evaluate the hematological safety profile of AQ therapy.Sprague-Dawley rats were randomly distributed into ...
Saka, W. A.   +3 more
openaire   +3 more sources

Neuroprotective effect of Manuka honey in Sprague-Dawley rats

open access: yes, 2022
   The data contained a quantitative dataset showing the effects of the lipopolysaccharide induced neuroinflammation on the hippocampi of Sprague-Dawley rats.
Victoria Verrall (13032162)
core   +1 more source

Keishibukuryogan is not carcinogenic in Sprague-Dawley rats

open access: yesJournal of Toxicologic Pathology, 2016
Keishibukuryogan is a traditional Japanese medicine widely administered to patients with menopausal symptoms. Because humans use it on a long-term basis, we believed that a carcinogenicity study was warranted. We orally administered keishibukuryogan (TJ-25) extract powder to 6-week-old Sprague-Dawley rats [Crl:CD(SD)], which were divided into four ...
Kanitani, Masanao   +3 more
openaire   +3 more sources

Phytochemical analysis and hepatoprotective activity of Raphanus sativus var. Sativus in Sprague-Dawley rats : hepatoprotective activity of Raphanus sativus var

open access: yes, 2020
Purpose: To determine the phenolic and flavonoid contents of R. sativus rhizome ethanol extract and the hepatoprotective effect of the extract in rats.Methods: Folin–Ciocalteau and aluminum chloride colorimetric tests were used to determine the contents ...
Amin, Kawa,
core   +1 more source

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