Results 51 to 60 of about 330,960 (360)

Sex Differences in the Reinstatement of Methamphetamine Seeking after Forced Abstinence in Sprague-Dawley Rats

open access: yesFrontiers in Psychiatry, 2015
Preventing relapse to drug abuse is one of the struggles faced by clinicians in order to treat patients with substance use disorders (DSM-5). There is a large body of clinical evidence suggesting differential characteristics of the disorder in men and ...
J. Ruda-Kucerova   +5 more
semanticscholar   +1 more source

High‐Spatiotemporal‐Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature‐Dependent Windows for Reversible Photothermal Neuromodulation

open access: yesAdvanced Functional Materials, EarlyView.
Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee   +9 more
wiley   +1 more source

Differences in Retinal Structure and Function between Aging Male and Female Sprague-Dawley Rats are Strongly Influenced by the Estrus Cycle

open access: yesPLoS ONE, 2015
Purpose Biological sex and age are considered as two important factors that may influence the function and structure of the retina, an effect that might be governed by sexual hormones such as estrogen.
S. Chaychi, Anna Polosa, P. Lachapelle
semanticscholar   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

Uninephrectomy in rats on a fixed food intake potentiates both anorexia and circulating cytokine subsets in response to LPS.

open access: yesFrontiers in Immunology, 2015
Recent human studies have suggested that mild reduction in kidney function can alter immune response and increase susceptibility to infection. The role of mild reduction in kidney function in altering susceptibility to bacterial lipopolysaccharide (LPS ...
Denis eArsenijevic   +3 more
doaj   +1 more source

Spontaneous Odontoameloblastoma in a Female Sprague Dawley Rat [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 2010
The present report describes a spontaneously developing, highly infiltrative, and expansile neoplasm in the mandible of a 9-month-old female Sprague Dawley rat. The lesion consisted of abundant odontogenic epithelium with induction of osteodentin in the adjacent mesenchyme and was classified therefore as an odontoameloblastoma. Odontoameloblastomas are
Eric R, Burrough   +2 more
openaire   +2 more sources

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr   +9 more
wiley   +1 more source

Spontaneous lactation in virgin Sprague-Dawley rats [PDF]

open access: yesLaboratory Animals, 1971
Spontaneous milky secretion was found in 24 out of 46 virgin female Sprague-Dawley rats aged 1 year which had been given 30 mg of 9,10-dimethyl-1,2-benzanthracene (DMBA) when 50 days old. The secretory activity was associated with hyperplasia both of mammary epithelium and connective tissue.
openaire   +2 more sources

Renalase Protects against Contrast-Induced Nephropathy in Sprague-Dawley Rats

open access: yesPLoS ONE, 2015
Background Contrast-induced nephropathy (CIN) is the third leading cause of hospital-acquired acute renal failure. Oxidative stress, apoptosis and inflammation play crucial roles in CIN.
Bing-hui Zhao   +5 more
semanticscholar   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

open access: yesAdvanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta   +4 more
wiley   +1 more source

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