Results 71 to 80 of about 334,934 (359)

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

EFFECT OF ALPHA TOCOPHEROL ON CHRONIC STRESS INDUCED DERANGEMENTS INN NEUROPEPTIDEY ON SPRAGUE DAWLEY RATS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To determine the chronic stress induced decline in plasma Neuropeptide Y (NPY) level and protective effects of Alpha Tocopherol (AT) on maintenance of Neuropeptide Y level. Study Design: Quasi-experimental study.
Saadia Zainab   +3 more
doaj  

Antihyperlipidemic effect of Berberis orthobotrys in hyperlipidemic animal models

open access: yesBangladesh Journal of Pharmacology, 2014
The present study was undertaken to evaluate antihyperlipidemic effect of aqueous methanolic extract of Berberis orthobotrys in experimentally induced hyperlipidemic animal models. Atorvastatin was used as standard drug.
. Alamgeer   +3 more
doaj   +1 more source

A Rat Treated with Mesenchymal Stem Cells Lives to 44 Months of Age [PDF]

open access: yes, 2016
There is a growing interest in the potential of mesenchymal stem cells (MSCs) for implementing regenerative medicine. We assessed the effect of intravenous administration of human bone marrow-derived MSC on the life span of a single Sprague-Dawley female
Goya, Rodolfo Gustavo   +4 more
core   +1 more source

Splenic Hemangiosarcoma in a Young Sprague-Dawley Rat

open access: yesJournal of Toxicologic Pathology, 2012
The present report describes a rare case of spontaneous hemangiosarcoma in a nine-week-old male Sprague-Dawley rat. At necropsy, multiple white nodules of various sizes were observed on and within the enlarged spleen and liver and were histopathologically determined to be composed of spindle- to oval-shaped cells that showed invasive growth without ...
Shiraki, Katsuhisa   +6 more
openaire   +3 more sources

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

The effect of 12 weeks of intermittent aerobic exercise on endothelin-1 concentration of plasma in adult rats

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: Endothelin is a vasoconstrictor which is released from the endothelium. The aim of the present study was to investigate the effect of intermittent aerobic exercise on the endothelin-1 concentration of plasma as an important indicator of ...
A Qassemian, M Koushki Jahromi
doaj   +2 more sources

Efek Protektif Ekstrak Etanol Umbi Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) terhadap Gambaran Histopatologi pada Sel Tumor Payudara Tikus Putih (Rattus norvegicus) Betina Galur Sprague Dawley Diinduksi 7,12 Dimethylbenz(α)Anthracene

open access: yesMajalah Kedokteran Andalas, 2023
Objective: To determine the effect of ethanol extract of dayak onion bulb on histology of mammary tumor cells in female Sprague Dawley rats strains that were induced by 7,12 dimethylbenz(α)anthracene (DMBA).
Afifah Nurkarnia
doaj   +1 more source

Changes in Pulmonary Arterial Wall Mechanical Properties and Lumenal Architecture with Induced Vascular Remodeling [PDF]

open access: yes, 2004
To explore and quantify pulmonary arterial remodeling we used various methods including micro-CT, high-resolution 3-dimensional x-ray imaging, to examine the structure and function of intact pulmonary vessels in isolated rat lungs.
Dawson, Christopher A   +3 more
core   +1 more source

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