Results 51 to 60 of about 247,912 (307)

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

open access: yesAdvanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang   +10 more
wiley   +1 more source

EFFECT OF ALPHA TOCOPHEROL ON CHRONIC STRESS INDUCED DERANGEMENTS INN NEUROPEPTIDEY ON SPRAGUE DAWLEY RATS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To determine the chronic stress induced decline in plasma Neuropeptide Y (NPY) level and protective effects of Alpha Tocopherol (AT) on maintenance of Neuropeptide Y level. Study Design: Quasi-experimental study.
Saadia Zainab   +3 more
doaj  

Antihyperlipidemic effect of Berberis orthobotrys in hyperlipidemic animal models

open access: yesBangladesh Journal of Pharmacology, 2014
The present study was undertaken to evaluate antihyperlipidemic effect of aqueous methanolic extract of Berberis orthobotrys in experimentally induced hyperlipidemic animal models. Atorvastatin was used as standard drug.
. Alamgeer   +3 more
doaj   +1 more source

Splenic Hemangiosarcoma in a Young Sprague-Dawley Rat

open access: yesJournal of Toxicologic Pathology, 2012
The present report describes a rare case of spontaneous hemangiosarcoma in a nine-week-old male Sprague-Dawley rat. At necropsy, multiple white nodules of various sizes were observed on and within the enlarged spleen and liver and were histopathologically determined to be composed of spindle- to oval-shaped cells that showed invasive growth without ...
Shiraki, Katsuhisa   +6 more
openaire   +3 more sources

The ontogeny of anxiety-like behavior in rats from adolescence to adulthood

open access: yes, 2010
Funding provided for Gillian Brown by Wellcome Trust grant 078405/Z/05/ZIn human beings, susceptibility to anxiety disorders can be relatively high during adolescence.
Lynn, Debra Alana, Brown, Gillian Ruth
core   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Neuronal function in male Sprague Dawley rats during normal ageing

open access: yes, 2017
During normal ageing, there are physiological changes especially in high energy demanding tissues including the brain and skeletal muscles. Ageing may disrupt homeostasis and allow tissue vulnerability to disease. To establish an appropriate animal model
Olagunju, J.A.   +2 more
core   +1 more source

Blood biochemical analysis and published reference values for biochemical analytes in male Sprague-Dawley rats.

open access: yes, 2021
Blood biochemical analysis and published reference values for biochemical analytes in male Sprague-Dawley rats.
Nuria Garcia-Carrillo (6729860)   +8 more
core   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

The effect of 12 weeks of intermittent aerobic exercise on endothelin-1 concentration of plasma in adult rats

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: Endothelin is a vasoconstrictor which is released from the endothelium. The aim of the present study was to investigate the effect of intermittent aerobic exercise on the endothelin-1 concentration of plasma as an important indicator of ...
A Qassemian, M Koushki Jahromi
doaj   +2 more sources

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