Results 11 to 20 of about 336,467 (360)
Home Cage Compared with Induction Chamber for Euthanasia of Laboratory Rats [PDF]
This study compared behavioral and physiologic changes in Sprague-Dawley and Brown Norway rats that were euthanizedby using a 30% volume displacement rate of CO2 in either their home cage or an induction chamber; rats euthanized in thehome cage were ...
Hickman, Debra L.
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Background Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive.
Astrid Skovmand +12 more
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Background: Hyperlipidemia can be defined as an increased concentration of lipids in the blood. Foxtail millet (FTM) is a nutrient-rich cereal containing several phytochemicals which have possible lipid-lowering and glucose-lowering abilities ...
Praneeth Reddy Onteddu +4 more
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Acute oral toxicity of zein nanoparticles with encapsulated gamma oryzanol in Sprague Dawley rats [PDF]
Gamma oryzanol (GO) is well known for its antioxidant activity and health-promoting benefits. The gamma oryzanol-loaded zein nanoparticles (GOZNs) were successfully prepared in our previous study. In the present work, the acute oral toxicity of GOZNs was
Rodsuwan Ubonphan +6 more
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Systemic candidiasis in Sprague-Dawley rats [PDF]
A reproducible model of a generalized Candida albicans infection was established in rats to allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the intravenous C. albicans model in mice, which serves as a primary model for in vivo efficacy studies of antimycotic compounds, the infectious process in Sprague-Dawley rats is ...
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Brain tumors induced in rats by human adenovirus type 12 [PDF]
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Matsuo, Keisuke +5 more
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Urolithiasis in the Sprague-Dawley rat [PDF]
A 7 year collection of calculi from short- and long-term studies with Sprague-Dawley rats showed that although the incidence of rats with urolithiasis was small (0·5%), the variety of sizes and composition of the calculi could be of general interest.
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Spontaneous Iron Overload in Sprague-Dawley Rats [PDF]
In a review of the toxicological studies performed in our laboratory during the period 1986-1995, we occasionally observed significant iron overloading in the liver. Liver tissue was examined by light and electron microscopy, and the results were analyzed by sex and age (7, 9, 11, 19, 31, 59, and 111 wk).
R, Masson, N O, Roome
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Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]
In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Borght, Karin van der, +4 more
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Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats [PDF]
The increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague-Dawley (SD) rats.We determined the ...
Buckley, A +17 more
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