Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases [PDF]
For studies requiring accurate conception-timing, reliable, efficient methods of detecting oestrus reduce time and costs, whilst improving welfare. Standard methods use vaginal cytology to stage cycle, and breeders are paired–up using approximately five ...
Agata K Stramek +18 more
core +1 more source
Strain specific effects of low level lead exposure on associative learning and memory in rats. [PDF]
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impairs the normal development of numerous cognitive and neurobehavioral processes.
Schneider, J. S., Verma, Megha
core +2 more sources
Spontaneous Nephroblastoma in 3 Sprague-Dawley Rats
SD系ラット3例に自然発生した腎臓腫瘍の病理組織学的検索を行った. 腫瘍は管を形成する一層の上皮性細胞と, その周囲に塊状に増殖する未分化な芽種性細胞から成り, 主に膠原線維から成る間質で分画されていた. この組織構築から腫瘍は腎芽腫と判断された. また, これらの上皮性細胞と芽種性細胞には電顕的に本質的な差を認めず, 組織構築が後腎胚種質に類似することと合わせ, 本腫瘍は腎実質上皮性の腫瘍であると考えられた.
T, Inui +4 more
openaire +3 more sources
Estudio comparativo de las fases de la hemostasia en dos líneas de ratas de laboratorio
El objetivo de la investigación fue comparar las fases de la hemostasia, en ratas de laboratorio de las líneas BIOU: Wistar y BIOU: Sprague-Dawley.
Lilibeth Navas +4 more
doaj
Spontaneous Teratoma in a Sprague-Dawley Rat
An 6-week-old male Sprague-Dawley rat which had undergone no experimental treatment died from enlargement of the abdomen. At necropsy, a spherical mass measuring about 3 X 4cm in diameter was connected to the retroperitoneal region cross to the middorsal line of the body.
T, Itoh, K, Shirota, N, Kagiyama
openaire +2 more sources
Atrioventricular Valvular Angiectasis in Sprague-Dawley Rats [PDF]
Subendothelial heart valve angiectasis has been reported in cows, dogs, pigs, rats, mice, and in human fetuses and newborns. We observed a high incidence (62 in 208 animals examined) of spontaneous angiectasis on the atrioventricular (AV) valves in 10– to 40–week-old Sprague-Dawley rats. The angiectasis was observed predominately on the septal cusp of
H, Fang +9 more
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Dysfunctional play and dopamine physiology in the Fischer 344 rat
Juvenile Fischer 344 rats are known to be less playful than other inbred strains, although the neurobiological substrate(s) responsible for this phenotype is uncertain.
Akopian +126 more
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Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P +11 more
core +1 more source
The neuroprotective effect of Sulindac after ischemia-reperfusion injury in rats [PDF]
PURPOSE: To investigate the neuroprotective effects of Sulindac on the hippocampal complex after global cerebral ischemia/reperfusion (I/R) injury in rats.METHODS: Thirty one Sprague-Dawley rats were used, distributed into group I (sham) n:7 were used as
Murat Cosar +10 more
doaj +1 more source
Safety evaluation of CuminUP60® – A novel curcumin complex
Curcuma longa L. is one of the most recognized Curcuma species (Sharifi-Rad et al., 2020 [3]). Curcumin, the primary polyphenolic compound found in turmeric has been used for a variety of purposes for centuries.
Margitta Dziwenka +9 more
doaj +1 more source

