Results 41 to 50 of about 200,564 (311)
INEL Spray-forming Research [PDF]
, 1992 Spray forming is a near-net-shape fabrication technology in which a spray of finely atomized liquid droplets is deposited onto a suitably shaped substrate or mold to produce a coherent solid.
Key, James F., Mchugh, Kevin M.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
MetalsSpray forming is a manufacturing process that enables the production of high-performance metallic materials with exceptional properties. Due to its rapid solidification nature, spray forming can produce materials that exhibit fine, uniform, and equiaxed ...
Lingfei Cao +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Spray-on technique simplifies fabrication of complex thermal insulation blanket [PDF]
, 1966 Spray-on process constructs molds used in forming sections of thermal insulation blankets. The process simplifies the fabrication of blankets by eliminating much of the equipment formerly required and decreasing the time ...
Bond, W. E. G., Raymond, R.
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Vision-aided Monitoring and Control of Thermal Spray, Spray Forming, and Welding Processes [PDF]
, 1993 Vision is one of the most powerful forms of non-contact sensing for monitoring and control of manufacturing processes. However, processes involving an arc plasma or flame such as welding or thermal spraying pose particularly challenging problems to ...
Agapakis, John E., Bolstad, Jon
core +1 more source
Breaking the Rayleigh-Plateau instability limit using thermocavitation within a droplet [PDF]
, 2013 We report on the generation of liquid columns that extend far beyond the traditional Rayleigh-Plateau instability onset. The columns are driven by the acoustic pressure wave emitted after bubble collapse.
Aguilar, G +5 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes +4 more
wiley +1 more source