Results 71 to 80 of about 53,283 (252)

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Taking a Newer, Faster, Intranasal Route: A Narrative Review of Transitioning to a Less-Invasive Rescue Treatment for Seizure Clusters

Patient Preference and Adherence
Jurriaan M Peters,1 Danielle A Becker,2 Sunita N Misra,3 Enrique Carrazana,3,4 Adrian L Rabinowicz3 1Department of Neurology, Harvard Medical School and Boston Children’s Hospital, Boston, MA, USA; 2Department of Neurology, The Ohio State University ...
Peters JM, Becker DA, Misra SN, Carrazana E, Rabinowicz AL   +4 more
doaj  

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Safety and Efficacy of 0.5% Carbomer 980 Gel for Treatment of Symptoms of Common Cold: Results of 2 Randomized Trials

Drugs in R&D, 2019
Background Two studies of intranasal 0.5% carbomer 980 gel were conducted evaluating nasal tolerability in healthy volunteers and safety and efficacy in adults with common cold symptoms.
Lara Dennie
doaj   +1 more source

Hydrogel Stack‐Tailored Logics and High‐Fidelity Multimodal Sensors Promoted by Precisely Evaluated Ionic Migration

Advanced Science, EarlyView.
Inspired by biological ion transport, this work introduces self‐powered multifunctional sensors utilizing tailored hydrogel stacks. Optimizing ionic migration with MXenes and carbon nanotubes achieves high‐performance energy harvesting and unique logic circuit functionality.
Haoran Chen, Hongjian Zhang, Zhonghui Shen, Taeuk Eom, Hyunseung Kim, Delong He, Jinbo Bai, Geon‐Tae Hwang, Yong Zhang, Chang Kyu Jeong   +9 more
wiley   +1 more source

Insight into the Relationship of Spray-Drying Conditions with the Physicochemical and Gelation Properties of Egg White Protein

Foods
This study aimed to provide systematic insight into the relationship between spray conditions and the physicochemical and gelation properties of egg white protein (EWP).
Yuying Hu, Yan Hu, Huiyi Wu, Luyang Bao, Xin Shi, Can Wu, Bing Cui, Hongshan Liang, Bin Zhou   +8 more
doaj   +1 more source

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

Advanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding, Wei Yang, Wenzhao Li, Guifang Xu, Yuanjin Zhao   +4 more
wiley   +1 more source

Rheology of spray-dried egg-yolk products

Grasas y Aceites, 2000
The emulsification process, as weIl as and the emulsion rheology and stability, greatly depends on the rheological properties of the continuous phase, the most important ingredient of which is yolk.
Juan Miranda, Antonio F. Guerrero, Pedro Partal   +2 more
doaj   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source