Results 41 to 50 of about 52,719 (293)
Gravitational Potential Energy per Unit Area as a Constraint on Archean Sea Level
Geochemistry, Geophysics, Geosystems, 2018 To constrain the density structure of Archean lithosphere, I assume that gravitational potential energy (GPE) per unit area at Archean spreading centers equals that for continents whose surfaces lay near sea level.
Peter Molnar
doaj +1 more source
Antigen presentation by B cells enables epitope spreading across an MHC barrier
Nature Communications, 2023 Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert +22 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Measurements and Models of Heat Flux and Plumes from Hydrothermal Discharges Near the Deep Seafloor [PDF]
Oceanography, 2012 Deep-sea hydrothermal vents are conduits of heat and chemicals from the lithosphere to the hydrosphere. Their plumes rise hundreds of meters from the seafloor into the water column; during their ascent, they entrain ambient water and are subject to cross
Daniela Di Iorio +7 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The East Pacific Rise Between 9°N and 10°N: Twenty-Five Years of Integrated, Multidisciplinary Oceanic Spreading Center Studies [PDF]
Oceanography, 2012 The East Pacific Rise from ~ 9–10°N is an archetype for a fast-spreading mid-ocean ridge. In particular, the segment near 9°50'N has been the focus of multidisciplinary research for over two decades, making it one of the best-studied areas of the global ...
Daniel J. Fornari +16 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Prediction, Verification, and Significance of Flank Jets at Mid-Ocean Ridges [PDF]
Oceanography, 2012 One aspect of ocean flow over mid-ocean ridges that has escaped much attention is the capacity of a ridge to convert oscillatory flows into unidirectional flows.
J. William Lavelle +4 more
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On the origin of the North Pacific arcs
, 2004 We present a new hypothesis that relates global plate tectonics to the formation of marginal basins, island arcs, spreading ridges and arc-shaped mountain belts around the North Pacific Ocean.
Rodríguez-Perea, Antonio +10 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source