Results 61 to 70 of about 67,757 (265)
Minimal wave speed of traveling wavefronts in delayed Belousov-Zhabotinskii model
Electronic Journal of Qualitative Theory of Differential Equations, 2012 This paper is concerned with the traveling wavefronts of Belousov-Zhabotinskii model with time delay. By constructing proper upper and lower solutions and applying the theory of asymptotic spreading, the minimal wave speed is obtained under the weaker ...
Shuxia Pan, Jie Liu
doaj +1 more source
Zika: The Formidable Speed of Viral Spread [PDF]
Berkeley Scientific Journal, 2016 ZIKA: THE FORMIDABLE SPEED OF VIRAL SPREAD BY MICHELLE VERGHESE I n 1947, deep inside the Zika Forest of Uganda, a group of scientists studying yellow fever happened upon something unexpected. A Rhesus monkey they were studying had developed a fever. However, the disease ultimately isolated from the monkey’s serum was certainly not yellow fever: it was
openaire +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Persistence of spreading speed for the delayed Fisher equation
Electronic Journal of Differential Equations, 2012 This article concerns the long time behavior of the delayed Fisher equation without quasimonotonicity. When the time delay is small and the instantaneous self-limitation effect exists, it is proved that the spreading speed is the same as that of the ...
Shuxia Pan
doaj
Industrial Crops and ProductsStraw biomass is an important agricultural renewable resource, and its shredding and field spreading are essential for sustainable agricultural development. This study investigates how internal airflow characteristics, airflow uniformity, and shaft-speed
Han Tang +6 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Traveling waves and spreading speed on a lattice model with age structure
Electronic Journal of Differential Equations, 2012 In this article, we study a lattice differential model for a single species with distributed age-structure in an infinite patchy environment. Using method of approaches by Diekmann and Thieme, we develop a comparison principle and construct a suitable
Zongyi Wang
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source