Results 51 to 60 of about 197,595 (287)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Analysis of OD Flows (Raw Data) [PDF]
, 2003 In a recent paper, Structural Analysis of Network Traffic Flows, we analyzed the set of Origin Destination traffic flows from the Sprint-Europe and Abilene backbone networks.
Crovella, Mark +5 more
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
FoodsThe increasing production of fruit and vegetable by-products from the food processing industry presents both environmental challenges and opportunities for valorisation as sources of bioactive compounds. These by-products, including peels, seeds, pomace,
Filomena Carvalho +2 more
doaj +1 more source
SPRINT: Ultrafast protein-protein interaction prediction of the entire human interactome
, 2017 Proteins perform their functions usually by interacting with other proteins. Predicting which proteins interact is a fundamental problem. Experimental methods are slow, expensive, and have a high rate of error.
Ilie, Lucian, Li, Yiwei
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Influence of recovery intensity on oxygen demand and repeated sprint performance [PDF]
, 2016 AIM: This study aimed to determine effects of recovery intensity (passive, 20, 30 and 40%V̇ O2peak) on oxygen uptake kinetics, performance and blood lactate accumulation during repeated sprints.
Babraj, J., Yamagishi, T.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Applied Sciences, 2021 Muscle architecture has been proposed as one of the most important determinants of muscle strength and power performance. The purpose of the present investigation was to correlate the muscle architecture with power, agility and maximal strength in ...
Sandro Bartolomei +5 more
doaj +1 more source
Physiological correlates of performance in international-standard squash players [PDF]
, 2009 Tactical, technical and fitness factors are important for success in elite squash. While tactical and endurance fitness aspects have been explored, altered demands that have resulted from rule changes and absence of specific tests of high-intensity ...
Cooke, Matthew +5 more
core