Results 61 to 70 of about 30,579 (262)

Body mass index and post-operative outcomes in older adults after major surgery

BMC Surgery
Background Up to 40% of major elective surgery are performed in older adults. Various frailty assessments have been developed to risk stratify older adults undergoing surgery. However, these are often complex and time-consuming to administer.
Jun Kiat Thaddaeus Tan, Wei Jing Fong, Sudha Harikrishnan, Ming Zhe Cai, Chin Jin Seo, Chin-Ann Johnny Ong, Chia Shulyn Claramae, Hairil Rizal Abdullah, Si Min Jolene Wong   +8 more
doaj   +1 more source

Rising Threats and Evolving Trends: Five Years of Urinary Tract Infection Prevalence in a Portuguese Hospital

Clinics and Practice
Background/Objective: Urinary tract infections (UTIs) are a significant public health concern worldwide, yet longitudinal data from Portuguese hospital settings remain limited.
Francisco José Barbas Rodrigues, Patrícia Coelho, Sónia Mateus, Miguel Castelo-Branco   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Influence of psycho-physiological indicators on the result of running on 200 m for high-qualified sprinters with visual impairment on the example of elite sportswoman

Здоров’я, спорт, реабілітація, 2018
The aim of the work is to reveal the influence of psycho-physiological factors on the individual performance in a track and field sprint among highly qualified athletes with visual impairment on the example of an elite athlete.
O.I. Chaika
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Relación entre la fuerza máxima en squat y acciones de salto, sprint y golpeo de balón. (Relationship among maximal strength in squat exercise, jump, sprint and kicking ball performance.) [PDF]

Revista Internacional de Ciencias del Deporte, 2008
ResumenEl objetivo del presente estudio fue analizar las posibles relaciones entre la fuerza máxima en squat y accionesexplosivas de salto, sprint y golpeo de balón.
Alfredo Arija Blázquez, Daniel Juárez Santos-García, José María González Ravé, Rosa María Aceña Rubio, Fernando Navarro Valdivielso   +4 more
doaj  

The Design of SPRINT MIND and SPRINT MIND 2020

Alzheimer's & Dementia
AbstractBackgroundThe Systolic Blood Pressure Intervention Trial (SPRINT) included a specific aim on the effect of blood pressure lowering the risk of cognitive impairment (mild cognitive impairment (MCI) and dementia). Early termination of the trial and fewer than expected cases left the study under powered to detect cases of probable dementia, but ...
Rapp, Stephen R., Supiano, Mark A.
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source