Results 61 to 70 of about 199,869 (309)

A mathematical modelling study of an athlete's sprint time when towing a weighted sled [PDF]

, 2013
This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/s12283-013-0114-2.This study used a mathematical model to examine the effects of the sled, the running surface, and the athlete on ...
A Murray, AJ Harrison, AJ Ward-Smith, AJ Ward-Smith, AJ Ward-Smith, AJ Ward-Smith, BNJ Persson, BT Crewther, CD Spinks, D Halliday, G Markovic, GJ Ingen Schenau Van, GM Duthie, J Cronin, J Cronin, JG Hay, LM Arsac, LM Arsac, Nicholas P. Linthorne, NP Linthorne, P-O Åstrand, PE Alcaraz, PS Maulder, S Jaric, UG Kersting, VM Zatsiorsky   +25 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Influence of recovery intensity on oxygen demand and repeated sprint performance [PDF]

, 2016
AIM: This study aimed to determine effects of recovery intensity (passive, 20, 30 and 40%V̇ O2peak) on oxygen uptake kinetics, performance and blood lactate accumulation during repeated sprints.
Babraj, J., Yamagishi, T.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Knowledge and thresholds for palliative care and surgery among healthcare providers caring for adults with serious illness

Frontiers in Medicine
IntroductionTimely palliative care and surgical interventions improve symptoms, health-related quality of life (HRQoL), and reduce medical cost for seriously ill adults at end of life (EOL).
Darryl Wen Kai Juan, Darryl Wen Kai Juan, Irene Ai Ting Ng, Irene Ai Ting Ng, Louis Choon Kit Wong, Louis Choon Kit Wong, Wei Jing Fong, Wei Jing Fong, Piea Peng Lee, Sui An Lie, Jamie Xuelian Zhou, Mingzhe Cai, Mingzhe Cai, Johnny Chin-Ann Ong, Johnny Chin-Ann Ong, Johnny Chin-Ann Ong, Johnny Chin-Ann Ong, Johnny Chin-Ann Ong, Jane Chin Jin Seo, Jane Chin Jin Seo, Claramae Shulyn Chia, Claramae Shulyn Chia, Claramae Shulyn Chia, Jolene Si Min Wong, Jolene Si Min Wong, Jolene Si Min Wong   +25 more
doaj   +1 more source

The acute effect of whole-body vibration on cycling peak power output [PDF]

, 2013
The aim of the present study was to determine if an acute bout of whole-body vibration (WBV) prior to sprint cycling would increase peak power output.
Hill, Colin
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Importance of Strategic Social Media Marketing

Expert Journal of Marketing, 2017
Technological innovation has grown at an unprecedented rate over the past couple of decades, creating multiple opportunities for marketing in online settings.
Simona VINEREAN
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

EFFECT OF FLYWHEEL WARM-UP ON LOWER BODY MUSCLE PERFORMANCE IN YOUTH ATHLETES [PDF]

Journal of Applied Sports Sciences
Post-activation performance enhancement (PAPE) is a phenomenon that has been used as a warm-up strategy to enhance subsequent muscular performance. The purpose of this study was to examine the efficacy of a flywheel warm-up to elicit a PAPE effect in ...
Liam Younger, Darryl Cochrane
doaj   +3 more sources