Results 51 to 60 of about 154,691 (289)

Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs [PDF]

open access: yes, 2018
Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well.
Seibel, Alex J.
core  

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

open access: yesAdvanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria   +7 more
wiley   +1 more source

Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord [PDF]

open access: yes, 2016
To restore function after injury to the CNS, axons must be stimulated to extend into denervated territory and, critically, must form functional synapses with appropriate targets. We showed previously that forced overexpression of the transcription factor
Balle, Eric   +8 more
core   +2 more sources

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

Exploring Responsible Research and Innovation (RRI) in youth mental health: reflections from researchers and young people

open access: yesResearch Involvement and Engagement
Background Responsible Research and Innovation (RRI) promotes inclusive, anticipatory, and reflexive research practices that respond to societal needs. While widely applied in technological fields, its application in youth mental health remains limited ...
Josimar Antônio de Alcântara Mendes   +8 more
doaj   +1 more source

Exploring the Role of Fibrin Gels in Enhancing Cell Migration for Vasculature Formation

open access: yesJournal of Functional Biomaterials
A hallmark of angiogenesis is the sprouting of endothelial cells. To replicate this event in vitro, biomaterial approaches can play an essential role in promoting cell migration.
Joana A. Moura   +5 more
doaj   +1 more source

Effects of Thermal and Non-Thermal Pre-Processing Methods on Physical Parameters of Jack bean (Canavalia ensiformis) Seed

open access: yesJournal of Applied Sciences and Environmental Management, 2018
Effects of thermal and non-thermal pre-processing methods on the physical parameters of jackbean seed were investigated. The bean was subjected to three pre-processing methods roasting and autoclaving which are thermal and sprouting a non-thermal pre ...
JO Odedeji   +3 more
doaj   +1 more source

Endothelial Cells Angiogenesis in Sulfated Glycosaminoglycan (GAG) Hydrogels Enhanced by Bioactive Glass‐Released Ions

open access: yesAdvanced Functional Materials, EarlyView.
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni   +13 more
wiley   +1 more source

Impact of Selected Storage Methods on Physical Properties of Potato (Solanum tuberosum L.) Tuber

open access: yesTurkish Journal of Agriculture: Food Science and Technology
Potatoes are starchy tubers consumed as staples in most parts of the world. Its storage is critical in preserving tuber quality, reducing post-harvest losses, and ensuring food security.
Thomas Okache   +2 more
doaj   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

open access: yes, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li   +9 more
core   +3 more sources

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