ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche +11 more
wiley +1 more source
Temporal Patterns of Allergen Sensitisation in the General Population: The LEAD Study. [PDF]
Lim CJM +6 more
europepmc +1 more source
Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios +24 more
wiley +1 more source
Is amniotomy a risk factor for severe perineal trauma? -A Swedish nationwide register study. [PDF]
Tallhage S +3 more
europepmc +1 more source
Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura +7 more
wiley +1 more source
Altered Intracellular Trafficking as a Mechanism for Prolonged Duration of G Protein-Coupled Receptor Activation. [PDF]
Kim TW +7 more
europepmc +1 more source
Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal +42 more
wiley +1 more source
KIF18A inhibitor prevents chromosomally unstable osteosarcoma growth by activating spindle assembly checkpoint. [PDF]
Yan Q +8 more
europepmc +1 more source
ABSTRACT Background IgE‐mediated food allergy burdens individuals, families and healthcare systems. Randomised controlled trials indicate early introduction and regular consumption of common food allergens in infancy can reduce food allergy risk. Few studies have explored parental and healthcare professional experiences. This systematic review examines
Karen Wright +14 more
wiley +1 more source
Food-induced anaphylaxis following skin prick testing: a case report and literature review. [PDF]
Novembre E +13 more
europepmc +1 more source

