Results 111 to 120 of about 117,266 (149)

Long‐Term Outcome of Fanconi Anemia Patients From the Italian Registry on Behalf of the Marrow Failure Study Group of the AIEOP (Italian Association for Pediatric Haematology‐Oncology)

American Journal of Hematology, EarlyView.
ABSTRACT We analyzed 193 Fanconi anemia patients from the Italian Registry, focusing on hematological outcome, cancer risk, and mortality, both in transplanted (n = 130, 67.4% of the cohort) and non‐transplanted (n = 63, 36.6% of the cohort) patients. After a median follow‐up of 7 years, almost all patients developed cytopenia that was more frequent in
Erica Ricci, Francesca Bagnasco, Filomena Pierri, Antonio Risitano, Piero Farruggia, Maura Faraci, Camilla Frieri, Paola Corti, Ugo Ramenghi, Walter Barberi, Giuseppe Menna, Giovanna Giagnuolo, Marta Pillon, Maurizio Miano, Paolo Di Bartolomeo, Marco Zecca, Elena Mastrodicasa, Rosamaria Mura, Beatrice Pinazzi, Laura Luti, Maria Licciardello, Angelica Barone, Marinella Veltroni, Giovanni Palazzi, Federico Verzegnassi, Francesca Patriarca, Daniela Onofrillo, Simone Cesaro, Roberta Ghilardi, Irene D'Alba, Rosa Angarano, Luca Arcuri, Andrea Beccaria, Ramona Tallone, Adriana Zatterale, Carlo Dufour   +35 more
wiley   +1 more source

Risk of Mortality From Esophageal Cancer Among US Poultry Workers, 1950−2019

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background While research suggests poultry industry workers have an increased risk of cancer mortality, little is known about their risk of esophageal cancer mortality. We investigated the association between working with poultry and esophageal cancer mortality while concurrently investigating other occupational and nonoccupational risk ...
Leanna Delhey, Christina Joshua, Jaimi L. Allen, Robert Delongchamp, Benjamin C. Amick, Wendy Nembhard   +5 more
wiley   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Advanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou, Rongbin Zhong, Zhonghui Luo, Hua Wei, Cui‐Yun Yu   +4 more
wiley   +1 more source

Low RYR2 Level Relates to Poor Prognosis of Patients With Lung Adenocarcinoma by Promoting Tumor Cell Proliferation and Inhibiting Immune Cell Infiltration

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Ryanodine receptor type 2 (RYR2) is a large calcium channel that has been identified as one of the most frequently mutated genes in lung adenocarcinoma (LUAD). Despite its potential significance, the role of RYR2 in LUAD remains poorly understood.
Tao Wang, Baozhen Wang, Zhongting Lu, Tao Li   +3 more
wiley   +1 more source

GDF10 Regulates Iron‐Dependent Lipid Oxidation in Colorectal Cancer Cells Through Interaction With IGF2

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Background: This study aims to identify genes with a high likelihood of genetic variation, significant expression differences, and prognostic implications in colorectal cancer (CRC) patients. The research also seeks to investigate the role and mechanisms of key genes in CRC through the analysis of health information data and a combination of ...
Kaobin Ouyang, Tianying Huang, Dan Xie, Hailin Xiong   +3 more
wiley   +1 more source

Effect of hydration schedules on dose‐limiting toxicity in patients with head and neck squamous cell carcinoma treated with cisplatin

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to determine if head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin chemoradiotherapy and short hydration (SH) experience less dose‐limiting toxicity (DLT) and receive more cisplatin than those with medium hydration (MH) or long hydration (LH).
Anouk W. M. A. Schaeffers, Cassimy B. van Neerven, Dorieke van Balen, Mirjam Crul, Marije Slingerland, Saskia A. C. Luelmo, Jan Paul de Boer, Jens Voortman, Arjan D. van Zuilen, Remco de Bree, Lot A. Devriese   +10 more
wiley   +1 more source

Squamous cell carcinoma appearing in X-ray-treated mycosis fungoides

, 1977
G Volden, TE. Larsen
openalex   +2 more sources

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source