Results 51 to 60 of about 674,966 (361)
Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience. [PDF]
, 2014 BackgroundActivated PI3K/AKT/mTOR pathway frequently occurs in metastatic or recurrent cervical carcinomas. However, the clinical benefits of matched therapy, a therapeutic approach targeting a specific mutational abnormality, have not yet been ...
Coleman, Robert L +11 more
core +3 more sources
Interleukin-1 receptor antagonist: a promising cytokine against human squamous cell carcinomas
Heliyon, 2023 Inflammation, especially chronic inflammation, is closely linked to tumor development. As essential chronic inflammatory cytokines, the interleukin family plays a key role in inflammatory infections and malignancies.
Yujie Ding +3 more
doaj
Genomic instability in human actinic keratosis and squamous cell carcinoma [PDF]
, 2011 OBJECTIVE: To compare the repetitive DNA patterns of human actinic keratoses and squamous cell carcinomas to determine the genetic alterations that are associated with malignant transformation. INTRODUCTION: Cancer cells are prone to genomic instability,
Cabral, Luciana Sanches +3 more
core +5 more sources
Technology in Cancer Research & Treatment, 2021 Objective We explored mechanism of microRNA-101-3p/Karyopherin α2 (KPNA2) axis in cervical squamous cell carcinoma. Methods: Bioinformatics methods were applied to identify genes for the study.
Hong Wang MM +2 more
doaj +1 more source
Psoriasin (S100A7) expression is altered during skin tumorigenesis [PDF]
, 2003 BACKGROUND: Psoriasin (S100A7) expression has previously been associated with psoriasiform hyperplasia as well as with tumor progression in breast cancer. Its expression profile for different stages of skin lesions is unknown.
A Mueller +36 more
core +3 more sources
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Hematoxylin and eosin stained oral squamous cell carcinoma histological images dataset [PDF]
arXiv, 2023 Computer-aided diagnosis (CAD) can be used as an important tool to aid and enhance pathologists' diagnostic decision-making. Deep learning techniques, such as convolutional neural networks (CNN) and fully convolutional networks (FCN), have been successfully applied in medical and biological research.
arxiv
Journal of Ovarian Research, 2018 Background Although cases of cervical squamous cell carcinoma metastatic to the ovary have been previously documented, we report the first case of superficially invasive squamous cell carcinoma metastatic to the ovary.
Minfen Zhang +6 more
doaj +1 more source
Expression of heparanase in basal cell carcinoma and squamous cell carcinoma [PDF]
Anais Brasileiros de Dermatologia, 2016 : Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer.
Maria Aparecida Silva Pinhal +5 more
doaj +1 more source
Prediction of post-radiotherapy recurrence volumes in head and neck squamous cell carcinoma using 3D U-Net segmentation [PDF]
arXiv, 2023 Locoregional recurrences (LRR) are still a frequent site of treatment failure for head and neck squamous cell carcinoma (HNSCC) patients. Identification of high risk subvolumes based on pretreatment imaging is key to biologically targeted radiation therapy.
arxiv