Results 71 to 80 of about 5,567,467 (249)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

Advanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer, H. Mutlu, C. Charmette, E. Randrianaridera, Z. Adaidi, R. Hedna, L. Pieuchot, I. Pluvy, K. Anselme, N. Couturier, J. P. Mericq, A. Ponche, I. Brigaud   +12 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Introduction: Esophageal Squamous Cell Carcinoma—Current Status and Future Advances

, 2020
Esophageal squamous cell carcinoma is the most common histological subtype of esophageal cancer. The carcinoma is more common in high-incidence areas such as in Central and Southeast Asia, Eastern and Southern Africa, South America, etc.
Lam, AK, Alfred K. Lam
core   +1 more source

Schistosomiasis and Urinary Bladder Cancer in North Western Tanzania: A Retrospective Review of 185 Patients. [PDF]

, 2013
Worldwide, cancers of the urinary bladder are well known to be associated with environmental chemical carcinogens such as smoking and occupational exposure to polycyclic aromatic hydrocarbons.
Chalya, Philipo L, Peter Rambau, Kahima Jackson, Philipo L Chalya, Jackson, Kahima, Rambau, Peter Fabian   +5 more
core   +1 more source

Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment

Advanced Science, EarlyView.
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo, Yijuan Wang, Dengwang Chen, Yinghan Zhang, Yi Shuai, Hualiang Yao, Tao Jiang, Hang Jiang, Ming Zhong, Xiangeng Wang, Ziwei Wang, Chenchen Xu, Ajay Goel, Hoi Tang MA, Feng Gao, Xin Wang   +15 more
wiley   +1 more source

Esophageal Squamous Cell Carcinoma: Methods and Protocols

, 2020
This volume provides current management and research protocols on oesophageal squamous cell carcinoma. Chapters guide readers through methods on clinical and pathological diagnostics, translational research for oesophageal squamous cell carcinoma, in ...
Lam, Alfred K
core   +1 more source

FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma. [PDF]

, 2012
PMCID: PMC3312909This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Ahmad Waseem (155362), Emilios Gemenetzidis (176601), Adiam W. Bahta (176614), Nadir, A, Ayesha Nadir, Ahmad Waseem, Deeviyaben Patel (176603), Gemenetzidis Emilios, Iain L. Hutchison (155346), Bahta, AW, Ayesha Nadir (176609), Hutchison, IL, Nadir Ayesha, Teh, MT, Iain L Hutchison, Muy-Teck Teh, Teh, M-T, Rameez Tariq, Gemenetzidis, E, Adiam W Bahta, Teh Muy-Teck, Muy-Teck Teh (155335), Patel, D, Emilios Gemenetzidis, Patel Deeviyaben, Waseem Ahmad, Tariq, R, Waseem, A, Deeviyaben Patel, Rameez Tariq (176604), Tariq Rameez, Hutchison Iain L., Bahta Adiam W.   +32 more
core   +2 more sources