Results 81 to 90 of about 593,407 (314)

Targeting phosphoinositide 3-kinase (PI3K) in head and neck squamous cell carcinoma (HNSCC). [PDF]

, 2018
The landscape of head and neck squamous cell carcinoma (HNSCC) has been changing rapidly due to growing proportion of HPV-related disease and development of new therapeutic agents.
Jung, Kyungsuk, Kang, Hyunseok, Mehra, Ranee   +2 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Prognostic implication of simultaneous anemia and lymphopenia during concurrent chemoradiotherapy in cervical squamous cell carcinoma

Tumor Biology, 2017
Radioresistance often leads to poor survival in concurrent chemoradiotherapy–treated cervical squamous cell carcinoma, and reliable biomarkers can improve prognosis.
Oyeon Cho, Mison Chun, Young-Taek Oh, O Kyu Noh, Suk-Joon Chang, Hee-Sug Ryu, Eun Ju Lee   +6 more
doaj   +1 more source

Expression patterns of α2,3-Sialyltransferase I and α2,6-Sialyltransferase I in human cutaneous epithelial lesions

European Journal of Histochemistry, 2013
Skin tumors have become one of the most common cancers in the world and their carcinogenesis is frequently associated with altered glycosylation patterns. The aberrant sialylation, a type of glycosylation, can mediate pathophysiological key events during
S.A. Ferreira, J.L.A. Vasconcelos, R.C.W.C. Silva, C.L.B. Cavalcanti, C.L. Bezerra, M.J.B.M. Rêgo, E.I.C. Beltrão   +6 more
doaj   +1 more source

A Rare Case of Synchronous Waldenström’s Macroglobulinemia and Cutaneous Squamous Cell Carcinoma with a Lung Mass: A Diagnostic and Management Dilemma

Case Reports in Oncology, 2020
Cutaneous squamous cell carcinoma has presented an increasing burden globally, with the occurrence of metastatic cutaneous squamous cell carcinoma being a relatively rare event but presenting with significant challenges in management, and a paucity of ...
Catherine Lynne Limberis, Simon Nayler, Bernardo Leon Rapoport   +2 more
doaj   +1 more source

Immunoregulatory Potential of Exosomes Derived from Cancer Stem Cells. [PDF]

, 2020
Head and neck squamous cell carcinomas (HNSCCs) are malignancies that originate in the mucosal lining of the upper aerodigestive tract. Despite advances in therapeutic interventions, survival rates among HNSCC patients have remained static for years ...
Abouyared, Marianne, Anderson, Johnathon D, Archard, Joehleen A, Belafsky, Peter C, Beliveau, Angela, Bewley, Arnaud F, Birkeland, Andrew, Clayton, Shannon M, Farwell, D Gregory, Rao, Shyam, Wagner, Joseph   +10 more
core   +1 more source

Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]

, 2019
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O., Ferlito, Alfio, Hellquist, Henrik, Hunt, Jennifer L.   +3 more
core   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]

, 2005
Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Bernier J, Budach W, Colevas AD, Colleoni M, Conti F, De Placido S, Degardin M, Dische S, Dobrowsky W, Gasparini G, Gralla R, Grau C, Haffty BG, Harrison LB, Hehr T, Kies MS, Koch WM, Munker R, Pouillart P, Poulsen MG, Regine WF, Shin DM, Siu LL, Vici P, Vokes EE, Wendt TG   +25 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source