Results 51 to 60 of about 90,842 (160)

A strategy for synergistic enhancement of immune circulation in head and neck squamous cell carcinoma by novel nucleic acid drug therapy and immunotherapy

Journal of Translational Medicine
Studies have shown that in the pathogenesis of head and neck squamous cell carcinoma, immune circulation obstruction caused by various factors including metabolic abnormalities, gene mutations, and matrix barrier, is a critical factor for the induction ...
Yangjian Hong, Yanyang Liu, Huize Shen, Bowen Li, Qinglin Li   +4 more
doaj   +1 more source

Eccrine porocarcinoma of the head: An important differential diagnosis in the elderly patient [PDF]

, 2008
Background: Eccrine porocarcinoma is a rare malignant tumor of the sweat gland, characterized by a broad spectrum of clinicopathologic presentations. Surprisingly, unlike its benign counterpart eccrine poroma, eccrine porocarcinoma is seldom found in ...
Akiyoshi E, Brenn T, Cho SB, Daniela Bruch-Gerharz, Dummer R, Goel R, Grimme H, Gunhan, Gutermuth J, Helmke B, Klaus-Werner Schulte, Lan CC, Matloub HS, Mishima Y, Perna C, Peter Arne Gerber, Pinkus H, Plunkett TA, Puttick L, Ritter AM, Robson A, Shaw M, Sigal R, Thomas Ruzicka, Valverde K, Wittenberg GP   +25 more
core   +1 more source

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck [PDF]

New England Journal of Medicine, 2016
Patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after platinum chemotherapy have a very poor prognosis and limited therapeutic options. Nivolumab, an anti-programmed death 1 (PD-1) monoclonal antibody, was assessed as treatment for this condition.In this randomized, open-label, phase 3 trial, we assigned, in a 2:1 ...
R. L. Ferris, G. Blumenschein, J. Fayette, J. Guigay, A. D. Colevas, L. Licitra, K. Harrington, S. Kasper, E. E. Vokes, C. Even, F. Worden, N. F. Saba, L. C. I. Docampo, R. Haddad, T. Rordorf, N. Kiyota, M. Tahara, M. Monga, M. Lynch, W. J. Geese, J. Kopit, J. W. Shaw, M. L. Gillison   +22 more
openaire   +5 more sources

Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma.

PLoS ONE, 2018
Fanconi anemia is a rare genome instability disorder with extreme susceptibility to squamous cell carcinoma of the head and neck and anogenital tract. In patients with this inherited disorder, the risk of head and neck cancer is 800-fold higher than in ...
Tuna Toptan, Marion G Brusadelli, Brian Turpin, David P Witte, Jordi Surrallés, Eunike Velleuer, Martin Schramm, Ralf Dietrich, Ruud H Brakenhoff, Patrick S Moore, Yuan Chang, Susanne I Wells   +11 more
doaj   +1 more source

Survival Prediction in Head and Neck Cancer: Impact of Tumor and Patient Specific Characteristics [PDF]

, 2012
Head and neck cancer accounts for almost 5% of all malignant tumors in the Netherlands. The most up‐todate Dutch Cancer Registry (NCR) database from 2009 reported 2878 new patients with an invasive carcinoma of the lip, oral cavity, pharynx and ...
Datema, F.R. (Frank)
core  

Fibroblast growth factor receptor 4 single nucleotide polymorphism Gly388Arg in head and neck carcinomas [PDF]

, 2019
BACKGROUND Head and neck squamous cell carcinoma (HNSCC) is considered to be a progressive disease resulting from alterations in multiple genes regulating cell proliferation and differentiation like receptor tyrosine kinases (RTKs) and members of the ...
Bergmann, C., Gires, O., Ihrler, S., Issing, W., Streit, S., Wimmer, E.   +5 more
core   +2 more sources

Genetic Susceptibility to Head and Neck Squamous Cell Carcinoma [PDF]

JNCI Journal of the National Cancer Institute, 1996
In addition to influences of exposure to carcinogenic compounds, the development of cancer may depend on an individual intrinsic cancer susceptibility. Biomarkers for cancer susceptibility can be powerful additions to epidemiologic analyses.This multicenter, case-control analysis combines previously published data and new data to substantiate the value
Cloos, Jacqueline, Spitz, Margaret R., Schantz, Stimson P., Hsu, T. C., Zhang, Zuo Feng, Tobi, Hilde, Braakhuis, Boudewijn J.M., Snow, Gordon B.   +7 more
openaire   +4 more sources

Synergy of electrochemotherapy and immunotherapy in the treatment of skin squamous cell carcinoma of the head and neck

Oral and Maxillofacial Surgery Cases, 2023
Treatment of advanced-stage head and neck cutaneous squamous cell carcinoma is a challenge for maxillofacial surgeons, oncologists, and radiotherapists.
Ida Barca, Francesco Ferragina, Elvis Kallaverja, Maria Giulia Cristofaro   +3 more
doaj   +1 more source

Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]

, 2019
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O., Ferlito, Alfio, Hellquist, Henrik, Hunt, Jennifer L.   +3 more
core   +2 more sources

A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck. [PDF]

, 2014
BackgroundAfatinib is an oral, irreversible ErbB family blocker that has shown activity in epidermal growth factor receptor (EGFR)-mutated lung cancer.
Blackman, A, Clement, PM, Cohen, EEW, Cupissol, D, Degardin, M, Del Campo, JM, Ehrnrooth, E, Fayette, J, Hitt, R, Seiwert, TY, Zhang, W   +10 more
core   +2 more sources