Neoplasia: An International Journal for Oncology Research, 1999 Replication-competent virus vectors are attractive therapeutic agents for cancer. G207, a second-generation, multimutated herpes simplex virus type 1 (HSV-1), is one such vector that is safe in primates and efficacious against human tumors in athymic ...
Ali Chahlavi +3 more
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Journal of Medical Case ReportsIntroduction Head and neck squamous cell carcinoma is the seventh most common type of cancer in the world. Metastases occur in up to 40% of cases, and bones are the second most frequent site.
Hamidreza Movahedi +7 more
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Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis [PDF]
, 2016 Human papillomavirus induced (HPV+) cancer incidence is rapidly rising, comprising 60–80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare, recurrent/metastatic disease accounts for nearly all related deaths.
Coppock, Joseph D +8 more
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The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model [PDF]
, 2012 One challenge of squamous cell carcinoma of the head and neck (SCCHN) chemotherapy is a small percentage of tumor cells that arrest in the G0 phase of the cell cycle and are thus not affected by chemotherapy. This could be one reason for tumor recurrence
Arnoldner, Christoph +6 more
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A Markov Model Approach to Predicting Regional Tumor Spread in the Lymphatic System of the Head and Neck [PDF]
Radiation planning for cancer therapy is becoming more and more dependent on the prediction of microscopic tumor spread to regional lymph nodes for its success.
Benson, Noah +2 more
core +1 more source
Mutation signature analysis identifies increased mutation caused by tobacco smoke associated DNA adducts in larynx squamous cell carcinoma compared with oral cavity and oropharynx. [PDF]
, 2019 Squamous cell carcinomas of the head and neck (HNSCC) arise from mucosal keratinocytes of the upper aero-digestive tract. Despite a common cell of origin and similar driver-gene mutations which divert cell fate from differentiation to proliferation ...
Curry, Joseph +9 more
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Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]
, 2016 The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita +5 more
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Re-irradiation for head and neck squamous cell carcinoma
Journal of the Egyptian National Cancer Institute, 2017 Introduction: Local recurrences after curative treatment have a potential for cure with salvage surgery or with re-irradiation. Methods: We reviewed the PubMed for articles published in English with key words squamous cell carcinoma, recurrent, re ...
Rony Benson +5 more
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Metastatic lymph nodes in the neck of patients with T1 and T2 squamous cell carcinoma of the lower lip detected with lymphoscintigraphy [PDF]
, 2013 Aims and backgroundThe aim of our research was to use lymphoscintigraphy as a main method to confirm and detect lymph nodes in the neck, in patients with squamos cell carcinoma of lower lip which were clinically T1, T2 and N0, and to justify the use of ...
Agani, Zana +4 more
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Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
, 2016 The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources