Results 91 to 100 of about 7,060,671 (294)

Comparative analysis of settlements green plantations classification in Ukraine and post-Soviet countries

open access: yesНаукові праці Лісівничої академії наук України, 2018
The aim of the paper is to assess the progressiveness and perfection of the modern functional classification of green spaces in settlements of Ukraine by comparing it with the one used earlier (in the 1950s) and the classifications currently used in ...
Vasyl Yukhnovskyi, Olga Zibtseva
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Refining Lagrange's four-square theorem

open access: yes, 2017
Lagrange's four-square theorem asserts that any $n\in\mathbb N=\{0,1,2,\ldots\}$ can be written as the sum of four squares. This can be further refined in various ways. We show that any $n\in\mathbb N$ can be written as $x^2+y^2+z^2+w^2$ with $x,y,z,w\in\
Sun, Zhi-Wei
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Vertical versus conical square functions

open access: yes, 2010
We study the difference between vertical and conical square functions in the abstract and also in the specific case where the square functions come from an elliptic operator.Comment: 21 ...
Auscher, Pascal   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Pittsburgh Rally Speech, Market Square [PDF]

open access: yes, 1984
Speech for campaign rally at Market Square, Pittsburgh, PA, November 5, 1984. Includes handwritten notes and diacritic marks.https://ir.lawnet.fordham.edu/vice_presidential_campaign_speeches_1984/1037/thumbnail ...
Ferraro, Geraldine
core   +1 more source

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